Global ETD Search
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Showing 1 to 4 of 4 for “"ApiAP2"”.
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Lifecycle Progression And The Sexual Development Of The Apicomplexan Parasite Cryptosporidium Parvum
… analyses further confirmed four sex specific ApiAP2 genes, and ApiAP2s in Plasmodium are involved in stage-specific development. We intend to disrupt sexual development by targeting one of these ApiAP2s, and cgd4_1110 was confirmed as an essential, female specific ApiAP2. We engineered …
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Interrogating Host-Parasite Dynamics During Plasmodium Liver Stage Infection
… were highly correlated to the expression of ApiAP2 transcription factors, containing mainly uncharacterized DNA binding motifs. Beyond transcriptional profiling, host cellular structure has been shown to be altered during P. berghei infection, but this has not yet been investigated during P. …
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Molecular Interactions between Apicomplexan Parasites and their Host Cells
… potential regulation of gene clusters by ApiAP2 transcription factors and found enrichment of mostly uncharacterized DNA binding motifs. This finding indicates potential liver-stage targets for these transcription factors, while also hinting at alternative uncharacterized DNA binding …
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AP2IX-4, a Cell Cycle Regulated Nuclear Factor, Modulates Gene Expression During Bradyzoite Development in Toxoplasma Gondii
Toxoplasma gondii is a ubiquitous, protozoan parasite contributing significantly to global human and animal health. In the host, this obligate intracellular parasite converts into a latent tissue cyst form known as the bradyzoite, which is impervious to the immune response. The tissue cysts …