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Showing 1 to 2 of 2 for “"Apelin system"”.
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Characterisation of the Apelin Receptor and its Endogenous Ligands, Apelin and Elabela/Toddler in the Cardio-Renal System
The apelin system is emerging as an important therapeutic target in several diseases. It comprises a G protein-coupled receptor, the apelin receptor, which binds two peptide ligands, namely apelin and Elabela/Toddler (ELA). Although apelin has been studied in some detail, little is known about the …
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The Identification and Pharmacological Characterisation of Novel Apelin Receptor Agonists In Vitro and In Vivo
The apelin system is an evolving transmitter system consisting of the G protein coupled apelin receptor and two endogenous peptide ligands, apelin and elabela. It is implicated as a potential therapeutic for a number of diseases; however, the endogenous peptides are limited by half-life and …