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Showing 1 to 2 of 2 for “"Apaf1"”.
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Structural and Spatiotemporal Organisation of Bax and Apaf1 during Apoptosis
… steps of apoptosis, Bax cluster formation and Apaf1 activation, using a combination of biochemical and microscopy approaches. I sought to better understand the contribution of spatial and structural protein organisation within cells towards the efficient promotion of apoptosis, an essential …
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DNA Damage-dependent Regulation and Function of akt-1 in Caenorhabditis elegans
… and the Apoptotic protease-activating factor 1 (Apaf1)-like adapter protein CED-4, respectively. Furthermore, PDK-1/PDK1 promotes germ cell apoptosis by a mechanism that does not include changes in the subcellular localization or absolute levels of CED-4/Apaf1, but does require the presence of …