Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 38 for “"Aortic stenosis"”.
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Predicting Aortic Stenosis Severity using Deep Learning
… cause of death globally. This thesis focuses on aortic stenosis, one of the most common and severe valve diseases. The evaluation of patients with suspected aortic stenosis includes echocardiography - an ultrasound based procedure that is used to visualize and evaluate the aortic valve. …
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Understanding and measuring flow in aortic stenosis with MRI
In patients with aortic stenosis, accurate assessment of severity with echocardiography is central to surgical decision making. But, when image quality is poor or equivocal results obtained, another robust non-invasive technique would be invaluable. Cardiac magnetic resonance (CMR) may be a useful …
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Assessment of aortic stenosis using modern non-invasive imaging techniques
INTRODUCTION: Aortic stenosis is characterised both by progressive narrowing of the valve and the hypertrophic response of the left ventricle. The purpose of this thesis was to study the contribution of inflammation and calcification to valve narrowing using Positron Emission and Computed …
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In silico and in vitro analysis of calcific and rheumatic aortic stenosis
Aortic stenosis (AS) is a valvular heart disease characterised by the narrowing of the aortic valve opening that restricts blood flow from the left ventricle to the aorta. AS is caused by different pathologies that each result in a specific valve opening morphology. The most common types of AS are …
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Cardiac magnetic resonance imaging assessment of aortic stenosis to improve clinical care
Background Aortic stenosis is the commonest valve disease requiring intervention in the developed world. Current guideline-based management strategies are based on historical observational data or expert opinion and may leave many patients with irreversible myocardial damage and adverse outcomes …
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Improving Preadmission Testing Nurses' Knowledge of Aortic Stenosis and Transcatheter Aortic Valve Replacement
… (PAT) nurses’ knowledge of severe/critical aortic stenosis (AS), transcatheter aortic valve replacement (TAVR) procedure and patient selection, and satisfaction with knowledge by 10%. Rapid growth of the TAVR program has contributed to a gap in nursing knowledge leading to inconsistent …
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The Surgical Management of Severe Aortic Stenosis In the Era of Transcatheter Aortic Valve Replacement
Transcatheter aortic valve replacement (TAVR) has emerged as a treatment option for severe and symptomatic aortic stenosis across the spectrum of surgical risk and has potentially transformed the surgical management of aortic stenosis. The objectives of this dissertation were: (1) To determine if …
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Neurohormonal and inflammatory markers in valvular heart disease
… to established histological evidence that aortic stenosis is an inflammatory disease. One hundred and sixty three patients with chronic valvular heart disease, including aortic stenosis (n=74), aortic regurgitation (n=40) and mitral regurgitation (n=49) underwent independent assessment of …
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Prognosis and Prognostic Factors in Aortic Valve Replacement for Aortic Stenosis // Прогноза и прогностични фактори при аортно клапно протезиране по повод на аортна стеноза
Калцификационната аортна клапна стеноза е хронично заболяване с прогресиращ ход. В крайния стадий на болестта се изявяват клинично белезите и симптомите на сърдечната недостатъчност и настъпва летален изход. Калцификационната аортна стеноза заема първо място, като причина за хирургично аортно …
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Fluid Dynamics Characterization of Transcatheter Aortic Valves
<p>Aortic stenosis due to degenerative calcific aortic valvular disease is the most reason for aortic valve replacement in developed countries. Aortic stenosis affects up to 7% of the world population, and current clinical data indicate that the number of the affected people could be triple by …
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Five cases of cardiovascular diseases: seen in a general medical ward during a clinical attachment
… infarction 3. Investigation of hypertension 4. Aortic stenosis and incompetence 5. Sudden death due to cardiac asystole
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Optimizing interventions for the treatment of vascular flow disruptions
… of a tissue is impeded and viability is lost. Aortic stenosis is a paradigmatic example of vascular flow disruption. In health there is no gradient across the aortic valve and pressure generated in the left ventricle is transmitted without loss to the aorta. Pressure gradients across the valve …
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Comparison of patient outcome for aortic valve replacement verses transcatheter aortic valve replacement
Aortic stenosis or narrowing of the aortic valve is the most common cause for surgical valvular replacement in the United States. The disease of aortic stenosis has a long asymptomatic latency period followed by a quickly progressing symptomatic phase. Symptoms of the disease include dyspnea, …
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Fully Coupled Fluid Structure Interaction Simulation of Bioprosthetic Heart Valves: A Numerical and Experimental Analysis
<p>Aortic stenosis impacts approximately 7% of the global population. In the past decade, the role of computational modeling has been becoming considerably important in the design of BHVs. To obtain reliable solutions in computational modeling, it is essential to consider accurate properties of …
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An interactive computer analysis of the aortic ejection click and first heart sound
The aortic ejection click and the first heart sound (S1) are described in the time and frequency domains from computer processed phonocardiogram data obtained from 13 valvar aortic stenosis patients and 6 normal ones. The interactive FOBTRAI program developed was capable of the following: (1) …
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Mitral insufficiency due to ruptured chordae tendineae
… heard unaccompanied by the slow rising pulse of aortic stenosis, the possibility of mitral insufficiency due to ruptured chordae tendineae should be considered.</p>
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Novel applications of fluorine-18 labelled radiotracers in cardiovascular disease
INTRODUCTION: Coronary artery, aortic valve and myocardial disease are important manifestations of cardiovascular disease responsible for a leading cause in cardiovascular morbidity and mortality in the UK and worldwide. In recent years the advent of non-invasive hybrid imaging through the …
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Earlier Detection of Antiphospholipid Syndrome
… over his eyes. He has a past medical history of aortic stenosis. He was taking Valsartan, Atorvastatin, B-12, Folic Acid, and Vitamin D-3 before the episode. He was prescribed Xarelto after the episode. It was found that he had an optical stroke. Since the pressure in the eye was relieved, …
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Predicting Transcatheter Aortic Valve Leaflet Thrombosis Risk Using Pre-Procedural Computed Tomography Angiogram and Computational Modeling
Aortic stenosis (AS) is a disease that affects nearly 3% of adults above the age of 65 and is characterized by narrowing of the aortic heart valve due to calcium buildup. It restricts blood flow from the heart and, if left untreated, can lead to irreversible damage to the left ventricle wall and …
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Transcatheter Aortic Valve Implantation: Risk Assessment and Clinical Outcome
Abstract Background: Transcatheter aortic valve implantation (TAVI) has emerged as a treatment for patients with aortic stenosis (AS) and high surgical risk. To date, reports of short- and mid-term survival have been favourable. The aim of this thesis was to evaluate early safety, risk assessment …
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