Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Aortic dissections"”.
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The Role of IL-6 in Inflammatory Aortic Aneurysmal Diseases
… vascular diseases including atherosclerosis and aortic aneurysms. Local vascular IL-6 secretion can be induced by dysregulated angiotensin II (Ang II) signaling, producing leukocyte infiltration that results in life-threatening aortic aneurysms and dissections. Precise mechanisms by which IL-6 …
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Mechanism of local IL-6 production and its role in accelerating vascular inflammation leading to aortic diseases
Vascular inflammation plays a significant role in aortic diseases and involves enhanced recruitment and local activation of circulating monocytes along with cytokine production, but the mechanisms responsible for these processes are unclear. The cytokine interleukin-6 (IL-6) is highly induced in …
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Fibroblasts: Key Cells in Inflammation and Fibrosis
… normolipidimic mice leads to the development of aortic dissections and abdominal aortic aneurysm (AAA). IL-6 is a pro-inflammatory cytokine that is secreted by fibroblasts and macrophages in the aortic adventitia and promotes the development of aortic dissections. In our previous work, analysis …
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Computational fluid dynamics as aid tool for the management of aortic wall diseases
Aortic aneurysms and dissections are pathological conditions affecting the aorta. Despite being different in clinical presentation, these pathologies share a high mortality rate, as well as a lack of reliable prognostic predictors. Local fluid dynamics is assumed to play a role in aortic …
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Effect of microstructure on mechanical behaviour of arterial tissue
… deaths caused by cardiovascular diseases (CVDs), aortic aneurysms (AAs) and aortic dissections (ADs) is more than from any other cause. Most CVDs are a result of atherosclerosis, in which a fibrous cap covered lipid-rich plaque is formed in the arteries. The fibrous cap can rupture, blocking the …