Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"AnxA1"”.
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Role of adipose tissue as an endocrineorgan in systemic inflammation
… regulated anti‐inflammatory protein, annexin A1 (AnxA1) and its role in fat tissue function; and Study 3: a double‐blind cross‐over randomised trial in 15 borderline metabolic syndrome males investigating the effect of a supplemental antiinflammatory agent, resveratrol (250 mg/day for two weeks, …
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Obesity-Induced Alterations in Sperm Quality, Testicular Morphology, and Extracellular Vesicle Localisation in Male Mice
… EV-specific biomarkers such as CD63, CD9 and ANXA1 were targeted. Frozen testes were utilised for EV extraction and further western blotting (WB) analyses. Spermatogenesis was investigated via WB for spermatogenesis-related proteins (IGF1, INSL6, and PRDX2). For EV extraction, frozen testes …
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Tyrosine Kinase Inhibitors in Triple Negative Breast Cancer
… 9 proteins were uniquely altered in 231-DasB. ANXA1, which has been implicated in breast carcinogenesis previously, was significantly increased in the variant cell line in response to dasatinib. While ANXA1 siRNA knockdown decreased proliferation in MDA-MB-231, it did not significantly alter …
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Polyclonal interactions in intestinal tumorigenesis
… in cancer stem cell identities with an Lgr5 and Anxa1 dichotomy. Importantly, this intratumoural heterogeneity in cancer stem cell identity corresponds to lineage marker territories, indicating that founder cell multiplicity can contribute to intratumoural heterogeneity that persists during the …
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Design, Synthesis and Evaluation of FPR-1 Antagonists in the Treatment of Glioma
High expression of FPR-1 and its ligands are known to contribute to glioblastoma development. It was hypothesised that antagonists that inhibit FPR-1 may effectively treat glioblastoma. The previously synthesised antagonist, ICT12035, was potent but only exhibited a moderate ability to penetrate …
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Design, Synthesis and Evaluation of FPR-1 Antagonists in the Treatment of Glioma
High expression of FPR-1 and its ligands are known to contribute to glioblastoma development. It was hypothesised that antagonists that inhibit FPR-1 may effectively treat glioblastoma. The previously synthesised antagonist, ICT12035, was potent but only exhibited a moderate ability to penetrate …