Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 35 for “"Antiretrovirals"”.
-
Drug-drug interactions between antiretrovirals and bedaquiline
… drug, however, potential drug interactions with antiretrovirals are a major concern. Bedaquiline is metabolized in the liver by an enzyme called cytochrome P450 3A (CYP3A). The antiretrovirals nevirapine, efavirenz, and lopinavir/ritonavir (LPV/r) can affect the activity of this enzyme, and …
-
Hiv And Antiretrovirals In The Central Nervous System: Molecular Mechanisms Of Cognitive Impairment
… potential in vitro and that neurotoxicity of antiretrovirals is highly variable both across and within drug classes. Neurotoxicity of one drug, lopinavir, was mediated by oxidative stress. Taken together, these data indicate that HIV and antiretrovirals may contribute to HAND persistence and …
-
The clinical role of therapeutic drug monitoring of antiretrovirals : a Cochrane systematic review
The objective of this study is to evaluate whether ARV TDM reduces mortality and morbidity of adult patients on cART.
-
The role of gender relations in decision-making for access to antiretrovirals. A study of the AIDS Support Organisation (TASO) clients, Kampala district, Uganda
The way gender relations influence access to care and treatment particularly access to antiretroviral medicines is a challenge to HIV/AIDS programmes and to the individuals and families with HIV. Gender norms that push women and men to adhere to dominant ideals of femininity and masculinity may …
-
HIV transmission to transmission to premature very low birth weight infants
… positive with all 5 mothers receiving inadequate antiretrovirals. Of the PCRnegative infants, 9 died and 87% of the survivors received further PCR testing which remained negative. With correct care, intrapartum transmission of HIV can virtually be eliminated.
-
Analysis of HIV early infant diagnosis and linkage to care in the Western Cape: a laboratory perspective
… HIV prevention programs. The principle of using antiretrovirals (ARV) to reduce the risk of transmission from mother to child is well established as a range of PMTCT regimens with varying efficacies have been widely studied and reviewed1. In South Africa and other Sub-Saharan countries, single …
-
The Public Sector HIV/AIDS Treatment Roll-out Campaign in the Western Cape: A case study highlighting success factors and challenges
… impossible. Drastically reduced prices for Antiretrovirals (ARVs) combined with substantial donor funding and the long-awaited adoption of a national treatment plan, have, however, shifted the debate. Now the question is not so much should universal ART be provided by government but, rather, …
-
Coverage of prevention of mother-to-child transmission services in Cape Town, South Africa
… specimens were tested for the presence of antiretrovirals.
-
The short-term outcomes of HIV-exposed versus HIV-unexposed very low birth weight infants
… especially if they are under-exposed to maternal antiretrovirals. Adequate maternal antiretrovirals may have a protective effect on incidence of necrotising enterocolitis and respiratory outcomes.
-
Biomedicalizing Risk: Technologies of HIV Prevention and the Moral Imperatives of Biological Citizenship
… a critical analysis of the prophylactic use of antiretrovirals for HIV, arguing that this practice represents a new relation of the body to risk, while potentially obscuring or normalizing structural conditions that contribute to vulnerability to infection.
-
Towards Rapid Measurement of Non-Nucleoside Reverse Transcriptase Inhibitors in a Portable, Low-Cost Platform
While antiretrovirals (ARV) for HIV prevention and treatment have become very effective over the last 40 years of development, many people living with HIV (PLWH) encounter inadequately suppressed viral loads and treatment failure. Providing drug-level feedback (DLF) can identify those with …
-
Willingness to pay for VCT and nevirapine for the prevention of mother to child transmission of HIV in the Kassena-Nankana district of Northern Ghana
… consequences of the HIV pandemic, There are antiretrovirals for the prevention of mother-to-child-transmission (PMTCT) and Nevirapine (NVP) is the cheapest, most feasible and highly cost-effective of all and suitable for resource poor settings. Voluntary Counselling and HIV Testing (VCT), …
-
Treatment of HIV associated neurocognitive disorders
… affect influx and efflux of drugs including antiretrovirals. Antiretrovirals that have better penetration into the CNS may result in improved cognitive function in patients with HAND, however this has not yet been conclusively shown. On the other hand, prolonged CNS exposure to high …
-
How Do Men Who Have Sex With Men Currently Understand, Evaluate And Respond To HIV Risk? A Mixed Methods Analysis Of An Internet Survey In A Post-Antiretroviral Society.
… structures, and sex, caused by the impact of antiretrovirals in the MSM communities. This study unified the results from quantitative and qualitative data that emerged from an online mixed methods survey to unravel the experiences of a convenience sample of 557 UK-based MSM. This survey …
-
Mechanisms of CCR5 Agonist/Antagonist Inhibition of HIV-1 Entry and In Vitro Selection of Virus Resistant to Maraviroc
Entry inhibitors represent a new class of antiretrovirals for the treatment of HIV-1 infection. These inhibitors target interactions of the viral envelope glycoprotein with host cell receptors as well as fusion of the viral and host cell membranes. Extensive development of inhibitors that target …
-
A Biophysical Investigation of HIV-1 Envelope Cytoplasmic-Tail Mediated Retention in the Gag Lattice
… interface that may be important for future antiretrovirals targeting the assembly of HIV. Lastly, I aim to provide a foundation for understanding the mechanistic interaction between Env-CT monomers and the Gag lattice by evaluating the retention and competitive properties of individual …
-
Acceptability of Antiretroviral Drugs among adults living in Chawama, Lusaka
Acceptability of Antiretrovirals (ARVs) has been found to be associated with several factors. In this study we investigated the level of willingness among adults living in Chawama and factors likely to be associated with willingness to taking ARVs This was a cross sectional study. Only eligible …
-
Acceptability of Antiretroviral Drugs among adults living in Chawama, Lusaka
Acceptability of Antiretrovirals (ARVs) has been found to be associated with several factors. In this study we investigated the level of willingness among adults living in Chawama and factors likely to be associated with willingness to taking ARVs This was a cross sectional study. Only eligible …
-
The politics of prison nursing and HIV/AIDS at Pollsmoor maximum security prison 1990-2008
… how legal activism catalyzed the provision of antiretrovirals (ARVs); this, alongside the work of NGOs such as HIV/TB Care, dramatically improved nurses' ability to provide HIV prevention and treatment services.
-
A retrospective review of risk factors for recalcitrant peptic structures
… did not affect recalcitrancy risk, taking oral antiretrovirals (ARVs) was significantly associated with PS recalcitrancy (p=0.032; OR 4.55). Presenting degree of dysphagia (p<0.001; OR 16), requiring more than 3 dilatations (p<0.001), and smaller index residual oesophageal lumen (p<0.001) were …
Page 1 of 2