Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Antiretroviral (ARV) therapy"”.
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Pharmacogenetics of Efavirenz response in Bantu-speaking South African HIV/AIDS patients
Efavirenz (EFV) is used in first-line antiretroviral (ARV) therapy of HIV-infected patients, and is principally metabolised by CYP1A2, CYP2A6, CYP2B6, CYP3A4/5 and the drug transporter ABCB1. Genetic variability in the above genes may contribute to differences in EFV plasma concentrations which …
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Condom use and HIV testing behaviours of men working in the construction industry in Western Cape, South Africa
… factors associated with the impact of someday antiretroviral (ARV) therapy initiation under Universal Test and Treatment (UTT), such as knowledge of where to obtain ARVs, were also found to directly influence the HBM and the TPB, underscoring the importance of the evolving social context of HIV …
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Profile of specific neurological and neurobehavioural problems in children with HIV-1 infection attending dedicated clinics
… - 12 yrs). Eighteen patients (23%) were not on antiretroviral (ARV) therapy at the time of testing. The Centre for Disease Control (CDC) immune categories of the patients at the time of assessment were: Category 1- n=6/80, Category 2- n=15/80 and Category 3- n=59/80. Thirty-three percent had a …
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The pharmacologenetics of lopinavir in a cohort of black African HIV/AIDS patients
… and prolonging life through the use of antiretroviral (ARV) therapy. Drugs used in ARV therapy target different major steps of the HIV reproductive cycle. These are nucleoside and non-nucleoside reverse transcriptase inhibitors (NRTIs/NNRTIs); fusion/entry inhibitors; integrase …
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Therapeutic and virological outcomes in adults living with HIV / AID at 6 and 12 months after initiation of first-line highly active antiretroviral therapy in an urban population in Namibia
Antiretroviral regimens have side effects that can threaten adherence by patients resulting in evolution of viral resistance due to suboptimal drug levels. Studies have shown that drug adherence of at least 80% can result in viral load suppression. There is no literature on the association between …
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Differential proteomic profiling towards elucidation of TB-IRIS pathogenesis
… syndrome (TB-IRIS) after addition of antiretroviral (ARV) therapy to anti-tuberculous therapy (ATT). The course can be prolonged and the average mortality rate is 2% (75% for TB-IRIS involving the central nervous system (CNS)). Immune elements – including neutrophils - involved in the …