Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 685 for “"Antiretroviral"”.
-
Adherence to highly active antiretroviral therapy among patients in the Keetmanshoop antiretroviral therapy programme, Namibia
… HIV patients in the public health sector. The antiretroviral treatment programme in Keetmanshoop started in October 2003. Adherence to treatment regimes in HIV care is a key factor in determining clinical outcomes and is associated with improved survival among HIV and AIDS patients. Sustained …
-
Supramolecular modification of selected antiretroviral drugs
A number of antiretroviral drugs that are currently in use for anti-HIV therapy have extremely poor aqueous solubility. This, along with the fact that many of these pharmaceutical compounds possess potential hydrogen bond donor and acceptor functionalities, makes them ideal candidates for attempted …
-
Toxicities associated with antiretroviral treatment of HIV-1
Background: Despite the success of antiretroviral treatment (ART) in human immunodeficiency virus (HIV), the associated toxicities are complex to manage and compromise treatment benefits. Prevention and treatment of chronic toxicities such as cardiovascular disease (CVD), metabolic disorders, …
-
PEPFAR, politics, and patients/antiretroviral treatment in Tanzania
Thesis (Ph. D.)--Michigan State University. Department of Anthropology, 2010
-
Adherence to paediatric antiretroviral therapy in South Africa
… der HIV-infizierten Kinder, die in Südafrika mit antiretroviralen Medikamenten behandelt werden, steigt drastisch. Das korrekte Befolgen der Therapie (die sogenannte Adhärenz) ist ein Schlüsselfaktor für deren Erfolg. Diese Studie untersuchte die Adhärenz von jungen ambulanten Patienten und führte …
-
The impact of antiretroviral therapy on tuberculosis incidence
Introduction Although HIV infection increases the likelihood of developing TB, evidence suggests that starting ART reduces the risk of TB incidence although not to the level of HIV negative people in the population. This study aims to determine the impact of ART on TB incidence in people living …
-
Longitudinal latent class and joint modelling of antiretroviral adherence
… investigates the relationship between antiretroviral therapy (ART) adherence and viral outcomes in people living with HIV in South Africa using advanced statistical modeling techniques. Utilizing data from the ADD-ART study, a prospective cohort of 238 adults on ART in Cape Town, the …
-
Evolution of sensory neuropathy after initiation of antiretroviral therapy
… the evolution of sensory neuropathy after antiretroviral therapy (ART) in human immunodeficiency virus–infected South Africans. Methods: Enrolment commenced before ART with 6-monthly follow-ups for 24 months. Symptomatic distal sensory polyneuropathy (SDSP) was defined as one symptom and …
-
Outcomes of infants starting Antiretroviral therapy in Southern Africa
Within the global burden of the Human Immune Deficiency Virus (HIV) stands a distinct group - HIV infected infants. They are a physically, physiologically, developmentally and socially vulnerable group who differ considerably from their adult and child HIV infected counterparts. Distinguished in …
-
HIV-1 protease as a target for antiretroviral therapy
Human immunodeficiency virus (HIV) is the causative agent of acquired immunodeficiency syndrome (AIDS). HIV employs three enzymes in its lifecycle, including a protease that enables maturation of polyprotein precursors. Despite decades of progress studying the lifecycle of HIV and elaboration of …
-
The Plasma, Whole Blood and Intracellular Concentrations of Antiretroviral Agents in South African Children Receiving Combination Antiretroviral Therapy with and without Concomitant Antitubercular Treatment
… and lopinavir/ritonavir (ratio 1:1) as part of antiretroviral therapy are used in combination with rifampicin-based antitubercular treatment in South African TB/HIV co-infected children. Adult studies show that concomitant rifampicin significantly reduces efavirenz and lopinavir plasma …
-
Acceptability of Antiretroviral Drugs among adults living in Chawama, Lusaka
Acceptability of Antiretrovirals (ARVs) has been found to be associated with several factors. In this study we investigated the level of willingness among adults living in Chawama and factors likely to be associated with willingness to taking ARVs This was a cross sectional study. Only eligible …
-
Acceptability of Antiretroviral Drugs among adults living in Chawama, Lusaka
Acceptability of Antiretrovirals (ARVs) has been found to be associated with several factors. In this study we investigated the level of willingness among adults living in Chawama and factors likely to be associated with willingness to taking ARVs This was a cross sectional study. Only eligible …
-
A metabolomics investigation of in utero antiretroviral exposure to neonates
… title "A metabolomics investigation of in utero antiretroviral exposure to neonates", deals with the concern over adverse metabolic consequences reported for some neonates prenatally exposed to antiretroviral treatment (HIV-ART). The pandemic due to HIV infection, the cause of AIDS, has become …
-
HIV, Antiretroviral Therapy, Pregnancy, Lactation and Bone Health in Uganda
… World Health Organisation recommends lifelong antiretroviral therapy (ART) for all HIV+ pregnant and breastfeeding mothers to prevent MTCT, and breastfeeding for ≥24 months for optimal child health in resource limited settings (Option B+ strategy). Initiation of ART in HIV+ adults is associated …
-
Chronic morbidities in perinatally HIV-acquired adolescents on antiretroviral therapy
… on ART were enrolled in the Cape Town Adolescent Antiretroviral Cohort (CTAAC) from seven health-care sites in Cape Town, South Africa, between July 2013 – April 2015. Eligibility criteria were adolescents, 9-14 years old, with perinatally acquired HIV, been on ART for at least six months, and who …
-
Morbidity from antiretroviral metabolic effects in Africa: The Mama Study
Introduction: Combination antiretroviral therapy (ART) has considerably reduced both the morbidity and mortality of Human Immunodeficiency Virus (HIV) infection and its associated complications, thus effectively transforming a fatal disease into a manageable chronic condition. However, the chronic …
-
Microneedle delivery for improved efficacy of antiretroviral and antibiotic drugs
Two classes of drugs, antiretrovirals and antibiotics, could benefit greatly from delivery through microneedles. Microneedles (MN) offer an increase in efficacy for these drugs by providing delivery to the lymphatic system through the skin, thus avoiding first pass metabolism and allowing more …
-
An economic evaluation of the impact of widespread antiretroviral treatment on secondary hospital in South Africa : case study of the GF Jooste Hospital Antiretroviral Referral Unit
… the current and anticipated impact of widespread antiretroviral treatment on the secondary hospital system in South Africa. The evaluation encompasses the treatment and care of HIV -positive inpatients and outpatients on or preparing for highly active antiretroviral therapy (HAART) at the …
Page 1 of 35