Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Antipsychotic agents"”.
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Concurrent Stimulant and Atypical Antipsychotic Drug Use in Children and Adolescents Diagnosed with Attention Deficit/Hyperactivity Disorder (ADHD)
… the concurrent use of stimulant and atypical antipsychotic agents in children and adolescents diagnosed with Attention Deficit/Hyperactivity Disorder (ADHD). Objectives: The goals of this study were 1) to examine the prevalence of and factors associated with concurrent use of long acting …
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Validation of an animal model of cognitive dysfunction associated with schizophrenia. Development and validation of the novel object recognition task using behavioural manipulations and psychotomimetic dosing regimens to induce cognitive deficits of relevance to schizophrenia in hooded-Lister rats.
… using carefully selected pharmacological agents. The aim of the studies in chapter 6 was to determine the effects of isolation rearing on cognitive performance in the NOR test following increasing ITIs. Additionally, the sensitivity of isolation reared rats compared to social controls …
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Neonatal Phencyclidine (PCP) induced deficits in rats: A behavioural investigation of relevance to schizophrenia.
… with acute treatment of typical and atypical antipsychotic agents. Results: Neonatal PCP treatment (10 & 20 mg/kg in males and 10 mg/kg in females; once a day for 3 days on PND 7,9 and 11) caused novel object recognition and spatial memory impairment in male and female rats both in the …
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Investigating Cerebellar Mechanisms of Schizophrenia by Using a Pharmacological Mouse Model: Regulation of Voltage-Gated Potassium Channels
… we describe the effectiveness of concomitant antipsychotic agents haloperidol and clozapine in attenuating the acute changes in behaviour induced by phencyclidine, and we introduce specific motor function tests to assess cerebellar involvement in the model. Together, these findings support …
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The prevalence of and factors associated with antipsychotic polypharmacy in patients with serious mental illness: Findings from a cross-sectional study in a low-middle income country
Rationale: Antipsychotic polypharmacy (APP) appears to be a common practice worldwide despite treatment guidelines advising against the practice for most patients in view of lack of evidence and possible risk of harm. Our study aimed to address deficiencies in local and international research by …
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Pharmacological Intervention Reduces Hippocampal Hyperactivity in a Mouse Model of Psychosis
… and it could become a candidate for testing antipsychotic drug activity. The subchronic DG inhibition causes a lasting downstream hippocampal hyperactivity, along with behavioral consequences. This doctoral dissertation examines the influence of antipsychotic and experimental compounds on …
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Der Einfluss von Ziprasidon auf den Schlaf und die Kortisolexkretion
Ziel der vorliegenden Arbeit war die Untersuchung des Einflusses von Ziprasidon auf den Schlaf und die Kortisolausscheidung bei gesunden Probanden unter einer ungestörten Bedingung und im Rahmen eines Insomnie-Modells. Die Probanden hielten sich hierzu zweimal für zwei aufeinander folgende Tage im …