Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Antihypertensives"”.
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Diagnoses behind prescribing of antihypertensives in lithuania: a cross-sectional study /
… antihypertensive drug class. Occasionally, antihypertensives are prescribed for diseases beyond hypertension, such as Type 2 diabetes mellitus, essential tremor, and chronic kidney disease (CKD). In some cases they were precribed for migraines, hyperthyroidism, etc. According to the research …
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Changes in the characteristics of approved New Drug Applications for antihypertensives
In this thesis, the control of hypertension provides the backdrop for my effort to investigate how clinical trial design has evolved for antihypertensive drug submissions reviewed and approved by the Food and Drug Administration between 1988 and 2001. To do this, I have constructed and undertaken a …
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Test of a Multidisciplinary Health Behavior Model of Medicare Elders' Antihypertensive Acquisitions
… elders were able to legally acquire their antihypertensives. When comparing the enhanced Health Belief Model (HBM) with the Pharmaceutical Acquisition Model for Medicare Elderly (PAMME) the HBM has 95.5 while 96.2 indicating slightly increased prediction with the added constructs of …
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Cross-country study on the promotion of new pharmaceutical products
… are classified as new and old generations and antihypertensives are classified as new, middle, and old generations in this study. Qualitative and quantitative methods are used to examine population, economic, price, promotional, regulatory, and cultural factors that contribute to the sales of …
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Commonly used medications and survival from ovarian cancer
… work has provided evidence in support of using antihypertensives and statins as possible therapies to improve survival for women with this disease. Both medication classes have been shown to reduce cancer progression and proliferation on a cellular level. Epidemiologic studies show a possible …
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Clinical assessment of arterial stiffness
… study, investigating the effect of antihypertensives on collagen turnover, suggested an association between increased collagen turnover and ACE-Is. Investigating the effect of ACE-I administration on arterial stiffness in subjects with PAD, we demonstrated an increase in collagen …
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Deprescribing for frail older adults residing in long-term care facilities: a mixed-methods evaluation
… was the most prevalent PIM criterion, with antihypertensives the largest drug class potentially inappropriately prescribed. The final deprescribing implementation strategy consisted of an education-enhanced 3-monthly multidisciplinary team deprescribing review, led by a nurse, conducted at …
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Genetic Predictors of Hyperglycemia Due to Hydrochlorothiazide Therapy
… in the Genetic Epidemiology of Responses to Antihypertensives (GERA) and Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) clinical trials. No SNP reached the <em>a priori</em> defined threshold of statistical significance (p<5x10<sup>-8</sup>). We detected 50 SNPs in 9 genomic …
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Factors associated with variation in secondary prevention medication use after stroke
… 80% use anticoagulants. Likewise, only 75% use antihypertensives, and 36% have documented blood pressure control. Cardiovascular co-morbidities were strongly associated with higher levels of medications use, whereas some mental health co-morbidities were associated with lower levels …
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Pharmacogenetics of resistant hypertension: evaluating the role of genetic variation in ABCB1, ADBR1, CES1, CYP3A4, CYP3A5, NEDD4L, NOS3, NR3C2 and SCNN1B among South African hypertensive patient
… with it, leading to increased efficacy of antihypertensives drugs such as enalapril. ADRB1 rs1801252G allele or ADRB1 rs1801252A>G - rs1801253G>C, G-C haplotype alters ADRB1 receptor function, leading to reduced sensitivity to beta-blockers such as atenolol and consequently reduced …
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Efecto del jamón serrano sobre determinados factores de riesgo cardiovascular.
… anti-inflammatory and antiaggregants, antihypertensives of any type (ACE inhibitors, angiotensin receptor blockers, etc.), previous surgery in the digestive system (gallbladder, intestine, etc.) / D, smoking, pregnancy or lactation. For the study two groups were configured as follows: …
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Studies of aldosterone renin ratio and genetic variation at the CYP11B1/CYP11B2 locus in human essential hypertension
… readings (p<0.001) in subjects not taking antihypertensives. The heritability of the ARR was 38.1% (p<<10-8), and the heritability of renin and aldosterone was 27.4% and 28.7% respectively with p<<10-8. Plasma aldosterone, but not ARR, was influenced by intron 2 conversion genotype in the …