Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 974 for “"Antigens"”.
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Immunologic Memory to Polysaccharide Antigens
… antibody response against previously encountered antigens. The clonal selection theory of acquired immunity attributes immunologic memory to the formation of an expanded compartment of quiescent antigen-specific memory B cells that are capable of rapid activation upon secondary antigen encounter. …
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Precipitating Antigens of Leptospira Pomona
Made available in DSpace on 2014-12-05T22:04:01Z (GMT). No. of bitstreams: 1 6200671.pdf: 4375998 bytes, checksum: 7af1a1894cac6915f151b556bd3303de (MD5) Previous issue date: 1961
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A study of treponemal antigens
… were found to contain a group of common antigens. The cross-reactivity was removed when the antisera was absorbed with Reiter cells. There was a second group of common antigens that were shared by the subspecies of T. socranskii, Treponeme D, and T. pectinvorum. Triton-extracts from …
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Soluble Antigens of Rat Uterine Homogenates and Their Serologic Relationship to Antigens of Other Tissues
Made available in DSpace on 2014-12-09T22:30:14Z (GMT). No. of bitstreams: 1 6711887.pdf: 3642411 bytes, checksum: 9d47839d60c73fdea86b02882b3d44ae (MD5) Previous issue date: 1967
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Structural Analyses of Murine Histocompatibility Antigens
<p>The major histocompatibility antigens are the predominant cell surface molecules recognized by the immune system in the rejection of grafts between individuals of the same species. The genes coding for the histocompatibility antigens are extremely polymorphic; the products of different alleles …
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Defining Tumorigenic Contributions of Meiotic Cancer-Testis Antigens
The general metadata -- e.g., title, author, abstract, subject headings, etc. -- is publicly available, but access to the submitted files is restricted to UT Southwestern campus access and/or authorized UT Southwestern users.
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Identification of protective rickettsial antigens for vaccine development
… CD8+ T cells. Defining specific T-cell antigens and correlates of protective cellular immunity are critical steps towards vaccine development for Rickettsia. However, these are major gaps in this field that are impeding progress towards a vaccine. In this investigation, I developed and …
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Blocking antigens of Shigella alkalescens and its variants
Thesis (M.S.)--Michigan State College of Agriculture and Applied Science. Dept. of Bacteriology, 1947
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Examining the Regulation and Function of Cancer Testis Antigens
Cancer Testis Antigens (CTAs) are a class of genes whose expression is generally restricted to the testis, but are reactivated in cancer cells. The function and regulation of many CTAs are unknown, however several CTAs have been shown to impact tumor cell fitness and correlate with poor prognosis. …
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Studies on the Immunogenicity of Ascaris Suum Larval Antigens
Made available in DSpace on 2014-12-12T01:27:34Z (GMT). No. of bitstreams: 1 7212185.pdf: 3991155 bytes, checksum: 782ce1f25c9b4d0fd450537c66d031f3 (MD5) Previous issue date: 1971
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Engineering Nanoparticulate Antigens for Enhanced Follicular Accumulation and Immunogenicity
In vaccine design, antigens are often arrayed in a multivalent nanoparticle form, but in vivo mechanisms underlying the enhanced immunity elicited by such vaccines remain poorly understood. In this thesis, we began by examining two model, HIV-immunogen-bearing nanoparticles that displayed an …
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The identification of prostate cancer associated tumour antigens and biomarkers
The widespread use of Prostate Specific Antigen (PSA) testing has resulted in the over detection and over treatment of potentially indolent disease due to the lack of specificity of PSA for prostate cancer (PCa). PROTEOMEX, a method of tumour associated antigen (TAA) identification, combines the …
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INTERNALIZATION AND IMMUNOGENICITY OF MUCOSALLY-ADMINISTERED SOLUBLE AND PARTICULATE ANTIGENS
… In order to elicit an immune response, mucosal antigens must traverse the epithelium and reach the sub-epithelial immune compartments. Understanding how antigens are internalized at mucosal surfaces and how the nature of antigen and the route of antigen uptake affect their immunogenicity would …
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CD4+ T cell response against food antigens in intestinal disease
… of the immune system is to distinguish harmless antigens, such as those found in food, from dangerous antigens. This process is known as oral tolerance and works very efficiently in healthy individuals, but it can also be disrupted, leading to food intolerances, allergies, celiac disease, or …
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Genetic identification of phage P22 antigens and their structural location.
Thesis. 1977. Ph.D.--Massachusetts Institute of Technology. Dept. of Biology.
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Tumor Antigens Revealed by Exome Seqeuncing Drive Editing of Tumor Immunogenicity
… tumor immunogenicity and provide evidence that antigens expressed by tumors drive the destructive or sculpting actions of immunity on cancers.</p> <p>Initial studies confirmed the finding that IFN-γ is a critical mediator of cancer immunoediting. Wild type mice treated with antibodies that …
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