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Showing 1 to 3 of 3 for “"Antigenic Cartography"”.
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Responding to an Evolving Pandemic: Characterisation of Emerging Evolving Viruses and Population Immunity by the Example of SARS-CoV-2
… I used computational methods developed for the antigenic characterisation of influenza virus to answer scientific and public health questions about SARS-CoV-2's evolution and population immunity, from the achievement of protection with the original vaccine designed against the ancestral Wuhan …
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Improving the analysis of surveillance antigenic data to support seasonal influenza vaccine composition recommendations
… One of the key inputs to this decision is the antigenic phenotype, measured by antibody titres using haemagglutination inhibition and virus neutralisation assays with ferret and human sera. Analyses of these data using antigenic cartography to produce a quantitative visualisation of antigenic …
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Predicting the Antigenic Evolution of Influenza Viruses with Application to Vaccination Strategy
… with similar antibody binding are said to be antigenically similar. Seasonal influenza viruses evolve antigenically over a timescale observable by humans. Vertebrate immune responses also adapt rapidly, such that a single infection usually leaves a host protected for life against antigenically …