Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Anticonvulsant Drug"”.
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The reduction of tolerance to the anticonvulsant effects of antiepileptic drugs
Tolerance has been shown to develop to the anticonvulsant effects of many different antiepileptic drugs. In some cases, tolerance to antiepileptic drug effects is so complete that the drugs become clinically ineffective, even at toxic doses. This is clearly problematic for the treatment of …
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The role of folic acid supplementation on exencephaly induced by maternal exposure to sodium valproate in the TO mouse
Valproic acid (WA) is an anticonvulsant drug known to cause spina bifida in humans and exencephaly in animals. The Theiler Outbred (TO) mouse exhibits a low incidence (4.4%) of spontaneous exencephaly at birth. This frequency is enhanced by sodium valproate (VPA), an anticonvulsant drug. Earlier …
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Gabapentin Discriminative Stimulus Effects
<p>Gabapentin (Neurontin®), an anticonvulsant drug, is primarily prescribed for neuropathic pain and epileptic seizures. Gabapentin is an inhibitor of the voltage gated calcium channel (VGCC) subunit α<sub>2</sub>δ-1. Due to its unique binding site, gabapentin is widely thought to have low abuse …
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The Mechanisms, Products, and Kinetic of Carbamazepine-Free Chlorine Reactions
Carbamazepine (CBZ) is an antiepileptic drug widely detected in drinking water supplies and wastewater effluent. It has been previously found that CBZ is recalcitrant to biological removal processes. Therefore, active CBZ will be exposed to wastewater effluent disinfection processes, which for most …
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Molecular Substrates And Neuronal Network Subserving Audiogenic Kindling In Genetically Epilepsy-Prone Rats
… associated with AGS kindling. Gabapentin is an anticonvulsant drug that is also effective in treating non-epileptic conditions such as anxiety disorders, ethanol withdrawal and neuropathic pain. The pathway connecting CeA to PAG has been implicated in the networks subserving these conditions. …