Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 42 for “"Anticoagulants"”.
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Synthetic, Sulfated, Lignin-Based Anticoagulants
<p>Chemoenzymatically synthesized low molecular weight lignin polymers have been previously found to be potent inhibitors of a number of serine proteases via allosteric mechanisms targeting heparin binding sites. Herein, we describe the creation of synthetic sulfated β-O4 lignin (SbO4L) polymer, …
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Use of direct oral anticoagulants in Scotland
… disorder, are treated long-term with oral anticoagulants in order to prevent strokes. As warfarin treatment is associated with several problems, the direct oral anticoagulants (DOAC) dabigatran, rivaroxaban, apixaban and edoxaban have been introduced. However, real-world information …
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Novel Sulfated 4-Hydroxycinnamic Acid Oligomers as Potent Anticoagulants
… of 4-hydroxycinnamic acids (DHPs) as potential anticoagulants. Oligomers were prepared through peroxidase-catalyzed oxidative coupling of 4-hydroxycinnamic acids. The products resulting from this reaction are called CDs, FDs and SDs. Structurally, these sulfated DHPs are unique and do not …
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Incidence of adverse drug events in COVID-19 patients on anticoagulants: a pharmacovigilance study
… events associated with the administration of anticoagulants in patients known to have COVID-19. Thus, it was hypothesized that with study of different anticoagulant drugs, there would be no significant difference in the observed adverse events for these drugs. Data for this study was obtained …
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Investigating prescribers' experiences of direct-acting oral anticoagulants for the management of nonvalvular atrial fibrillation.
Direct-acting oral anticoagulants (DOACs) have relatively recently been licensed for stroke and systemic embolism prevention in patients with non-valvular atrial fibrillation (AF) and have replaced warfarin as the first line agent of choice. The aim of this research was to determine prescribers' …
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Increasing Patient Satisfaction and Decreasing Hospital Readmission Due to Deep Venous Thrombosis by Providing Anticoagulation Education for Orthopedic Patients
… high risk to develop DVT postoperatively, proper anticoagulants and anticoagulation education is an important aspect of patient care. By implementing a well-designed and easy-to-read patient handout on anticoagulants with instructional script for nurses will empower patients to achieve higher …
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Investigations into the fibrinolytic system and haptoglobin types in certain hereditary and acquired haemostatic disorders and the presence of circulating anticoagulants in such states
I THE FIBRINOLYTIC SYSTEM: A review of the literature is presented together with an evaluation of the present methods for the measurement of its parameters.
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A study of the impact of substituting Warfarin with Direct Oral Anticoagulants (DOAC), in Atrial Fibrillation (AF) patients over 65 years old: The Patients’ and Clinicians’ Perspectives.
… the newer medication referred to as Direct Oral Anticoagulants (DOACs) was less broadly studied. Importantly, little was known about how patients coped on a daily basis with this new treatment. Furthermore, the practical and social impact of a switch from Warfarin to a DOAC for clinical reasons …
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Development of guidelines for high-risk medication dispensing
… the HiRisk documentation sheet, the direct oral anticoagulants rivaroxaban and apixaban were the most commonly dispensed (n=20) high-risk medications followed by warfarin (n=11) and insulin (n=7). Throughout the dispensing process, all pharmacists (N=50) ensured that patients understood well how …
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ESTUDO COMPARATIVO DO EFEITO DA AMBIENTAÇÃO E DOS ANTICOAGULANTES EDTA E CITRATO DE SÓDIO SOBRE A AGREGAÇÃO PLAQUETÁRIA EM AMOSTRAS SANGUÍNEAS DE GATOS DOMÉSTICOS
… research was to analise the aclimatation and two anticoagulants effects on platelet aggregation and compare the manual and automatic platelet counting methods in blood samples of cats. One group of ten animals was submitted to a pre blood collection aclimatation under the effects of a facial …
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Designing Direct and Indirect Factor Xa Inhibitors
<p>Anticoagulants are the basis for treatment and prevention of thrombotic diseases. The currently available medicines are associated with a wide range of adverse reactions that mandates developing new anticoagulants. Several lines of evidence support the superiority of factor Xa (FXa) as a …
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Antithrombotic agents under flow conditions
… agents: anti-platelet antibodies and anticoagulants, including unfractionated heparin (UFH), low molecular weight heparin (LMWH) and hirudin. <br></br><br></br>Increasing flow rates increased TG, which was higher in the presence of ECM than in the presence of HUVEC. All anti thrombotic …
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Adverse drug reactions in hospital inpatients
… used drugs such as opioids, diuretics and anticoagulants were the most frequent causes of ADRs. Bleeding, renal impairment and Clostridium difficile were the ADRs with the greatest impact on patient length of stay and thus should be key areas for intervention strategies. Adoption of methods …
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New interpretable machine learning techniques and an application to stroke prediction in atrial fibrillation patients
… a prior history of stroke and who are not taking anticoagulants. The first part of the thesis presents an interpretable machine learning algorithm that can be used as an alternative algorithm to the decision tree algorithm. Our algorithm builds an optimized rules list model from data by maximizing …
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Biochemical Evaluation of Lignin-like Molecules
<p>Current anticoagulants carry a serious risk of bleeding complications. In addition, narrow therapeutic index, drug interactions, immunological reactions, toxicity and high cost to benefit ratio limits the effective use of these drugs in patients with thrombotic conditions.Heparin is the most …
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Retrospective evaluation of the rockall risk scoring system in patients with nonvariceal upper gastrointestinal hemorrhage at a community hospital
… evaluated whether certain antiplatelet agents, anticoagulants, and NSAIDS affected the Rockall scores. The Rockall scoring system identified 21% of patients as having low Rockall scores, with no significant differences in length of stay between risk groups. Our study shows that identifying …
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A Minimally Invasive Ultrasound Therapy Based On Time- Reversal Acoustics For The Treatment Of Deep Vein Thrombosis
… Traditional DVT treatments have relied on using anticoagulants to prevent the recurrence of DVT but not in its treatment. Here we have developed a minimally invasive model that uses low-powered ultrasound as a therapeutic aid. We have used the principles of time-reversal acoustics to develop an …
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Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension
… effects of treatment with vasodilators and oral anticoagulants, and the results of heart and lung transplantation in the PPH group; 3. Attempt to identify features which could be used to predict prognosis in PPH; and thereby 4. Define criteria for selecting PPH patients whose prognosis could be …
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Factors associated with variation in secondary prevention medication use after stroke
… to lower blood pressure, and anti-platelets or anticoagulants to reduce the risk of clotting, yet many patients do not take them. In this thesis, I investigated which stroke and TIA survivors are missing out on stroke prevention medications. First, a systematic review and meta-ethnography …
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Analýza lékových problémů ("drug-related problems) v ambulanci lékaře II.
… hlavně léčiva skupiny DOAC - direct oral anticoagulants - a jejich lékové problémy. Obsahem praktické části je pak samotná analýza lékových problémů vyskytujících se v ordinaci praktického lékaře. Cíl: Teoretická část - popsat proces hemostázy a možnosti ovlivnění tohoto procesu léčivy. …
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