Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Anticancer mechanisms"”.
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Investigation of anticancer activity and mechanisms of Meso- 2,3-dimercaptosuccinic acid (DMSA) in glioblastoma cell lines
… FDA approved anti alcoholism drug has excellent anticancer activity against a wide range of cancers with its metal binding capability through its unique dithiol structure. Hence our group is interested in identifying clinically used dithiol compounds which are structurally similar to DS and has …
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Investigation of the anti-breast cancer efficacy and mechanisms of disulfiram
… acquired resistance of BC cells to conventional anticancer drugs. Cancer stem cells (CSCs) have been thought to be responsible for the chemoresistance. My study demonstrated that mammospheres manifested CSC characteristics and are highly resistant to several first line anti-BC drugs. This may be …
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Investigation of chemoresistant mechanisms in triple negative breast cancer cell lines and development of a nano-enabled Disulfiram for breast cancer treatment
… de novo and acquired resistance to conventional anticancer drugs is a major limitation and cause of therapeutic failure. Cancer stem cells (CSCs) are believed to be responsible for chemoresistance and tumour relapse. My study demonstrates that hypoxia is involved in the development and …
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Curbing environmental pollution of water hyacinth by using it in drug discovery
… in literature, however, the description of its anticancer mechanisms is limited and information on its potential for male contraceptive application is lacking.<br/><br/>This study set out to find alternative uses for water hyacinth by exploring gaps in drug discovery and the objective was to; …