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Showing 1 to 2 of 2 for “"Antibody mimics"”.
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Design and applications of antibody mimics against epidermal growth factor receptor
… These limitations have led to the research for antibody alternatives with lower molecular weight, similar binding and affinity properties but without the lengthy and complicate process of generating antibodies. Some examples of these efforts include minibodies, fragment antigen binding (FAB), …
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Rational design, characterization and in vivo studies of antibody mimics against HER2
… and Knob-Socket model can be developed to design antibody mimics for targeting HER2. All designed antibody mimics were simulated and docked with HER2 using Molecular Operating Environment (MOE) software to estimate binding energy and analyze the detail interaction map. A series of mimics were then …