Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Antibody maturation"”.
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Computational modeling of protein-biomolecule interactions with application to mechanotransduction and antibody maturation
… computed to improve binding affinity of an antibody-small molecule complex with relevance to cancer treatment. Our calculations suggested several beneficial mutations for experimental characterization. The work illustrates the value of computational modeling for understanding …
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Computational modeling of protein-protein and protein-peptide interactions
… protein modeling, including the study of antibody maturation mechanisms, and the development of protocols for peptide-protein interaction prediction and template-based modeling of protein complexes. The first project, a comparative analysis of docking an antigen structure to antibodies …
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Acyloxyacyl Hydrolase: Studies on Its Regulation and Function in Mus Musculus
… with IL-4, IL-1ᬠTNFa and an agonistic CD40 antibody (maturation cocktail), and increased following treatment with microbial agonists that engage 3 distinct Toll-like receptors (LPS, TLR4; CpG oligodeoxynucleotides, TLR9; and a Gram-positive bacterium (Micrococcus luteus), TLR2). Maturation …