Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Antibody conjugation"”.
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CD133 Antibody Conjugation to Decellularized Human Heart Valves For Circulating Endothelial Progenitor Cell Capture
… this study is to examine the capacity of CD133 antibody-conjugated valve tissue to capture circulating endothelial progenitor cells (EPCs). Decellularized human pulmonary valve tissue was conjugated with CD133 antibody at varying concentrations and exposed to CD133 expressing NTERA-2 cl.D1 (NT2) …
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Point-of-care immunoassay system using carbon nanotube labels
… surface of the CNTs for uniform dispersion and antibody conjugation in aqueous solution. Surfactant assisted dispersion of the CNTs was studied using PVP and PEG. Covalent conjugation of antibodies on the carboxyl groups of the CNTs was accomplished using EDC/Sulfo-NHS coupling chemistry. The …
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Engineered Type 1 Conventional Dendritic Cell–Based Therapies for In Situ Cancer Immunization
… or in vivo targeting approaches utilizing antibody conjugation. However, antigens mismatch and suboptimal dendritic cell function may limit therapeutic efficacy. Type 1 conventional dendritic cells (cDC1s) are dendritic cell subsets specialized for cross-presentation and CD8+ T cell …
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Extracellular Vesicle Capture and microRNA Detection
… the thiol-acrylate Michael addition reaction for antibody conjugation and optimized it for extracellular vesicle capture. Using these porous, antibody functionalized hydrogel particles, we captured breast cancer serum and match healthy serum extracellular vesicles using two surface markers, paving …
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Probing the distribution of gliadin proteins in dough and baked bread samples using conjugated quantum dots as a labeling tool
… was investigated. QDs were conjugated to gliadin antibody and used as a fluorescent probe to track gliadin protein in dough and baked bread samples. The type and quantity of gluten proteins and their subfractions, gliadins and glutenins, are critical for baked product functionality. Gliadin …
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Development of novel antibody-targeted nanoparticle strategies for treatment of pancreatic cancer
… receptor-5 (DR5) pathway using the monoclonal antibody conatumumab (AMG 655). However, the results of these clinical trials proved disappointing with no survival advantage being observed. Subsequent literature has suggested that this was most likely due to inadequate receptor clustering and …
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Single-molecule G-quadruplex visualisation in live cells and 3D chromatin
The G-quadruplex (G4) is a secondary DNA structure formed by the self-assembly of guanine nucleotides. Mapping G4 formation in the human genome shows that they are enriched in functionally important regions such as promoters, enhancers, transcription factor and architectural protein binding sites. …