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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 116 for “"Antibody Production"”.
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Targeting Proteins of Aspergillus fumigatus for Monoclonal Antibody Production
IA is increasingly prevalent and problematic among patients with immunodeficiency. Early diagnosis of IA can be difficult because the symptoms patients display are not specific to fungal infections, and the diagnostic tests currently in use are unreliable. It is well known that the organisms that …
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The significance of antibody production in human renal transplantation
… PRA-STAT. These methods were used to investigate antibody production in patients with failed transplants. Flow cytometric analysis of antibody binding to pooled cells was found to be a reliable and sensitive method for the detection of HLA class I and class II specific antibodies. PRA-STAT also …
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The Effects of Cyclohexylamine on Antibody Production in Rabbits
… To understand the effects of cyclohexylamine on antibody production in rabbits, a group of rabbits was given intraperitoneal injections of cyclohexylamine hydrochloride (CHA-HCL) at a concentration of 50 mg/kg/day. After 70 days of treatment with CHA-HCL, the animals were assayed for total gamma …
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Antibody production with synthetic peptides against human Coronavirus-NL63 ORF3 protein
… BALB/c mice. Antigen-specific ELISA assessed the antibody specificity and sensitivity. The mAbs that exhibited the highest specificity and sensitivity for antigenic peptide (s) were used to characterize the ORF3 protein by Western blot and immunofluorescence analysis (IFA).
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Molecular dynamics of monoclonal antibody production in high density perfused bioreactors
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Applied Biological Sciences, 1992.
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MOLECULAR ROLES OF HSP27 IN IMPROVING MONOCLONAL ANTIBODY PRODUCTION OF CHO CELLS
… ARE THE MAMMALIAN CELL LINES OF CHOICE FOR THE PRODUCTION OF RECOMBINANT THERAPEUTIC BIOLOGICS INCLUDING THE RAPIDLY EXPANDING MONOCLONAL ANTIBODIES (MAB) AND BIOSIMILARS. THERE ARE OPPORTUNITIES TO EXPLORE THE USE OF ENGINEERED CHO CELL LINES WITH IMPROVED RECOMBINANT BIOLOGICS CAPABILITIES. …
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Rate of hemolytic antibody production by single cells in vivo in rabbits
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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The biochemical dynamics of monoclonal antibody production in high density perfused fermentors
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Applied Biological Sciences, 1992
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Characterization of the down regulation of antibody production in high cell density perfusion culture
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Applied Biological Sciences, 1994.
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Cellular requirements for antibody production in a novel LPS-enhanced model of autoimmune myasthenia gravis
… that LPS abrogated B cell differentiation\r\nto antibody secreting cells in the LPS-EAMG model. Furthermore, CD8-/- mice were\r\nalso susceptible to the development of LPS-EAMG, but were resistant to the development of moderate or severe signs of EAMG. While CD8 deficiency did not affect the …
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Immunomodulatory effects of dietary fibre supplementation: effects on cytokine and antibody production and lymphocyte population profiles
Gastrointestinal microflora has been shown to have a bi-directional relationship with the host immune system. A variety of fermentable carbohydrate polymers largely pass through the small intestine, providing fermentable substrates for gut microflora. Dietary fibre supplementation may provide a …
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Comparison of the growth and monoclonal antibody production of suspended mammalian cells in three perfusion systems
… survey of bioprocess options for typical drug production vehicles in the biotechnology industry. This goal was accomplished by comparing the growth and monoclonal antibody production by HPCHO Chinese hamster ovary cells and IB4 hybridoma cells in batch, fed-batch, and three perfusion systems: …
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The relationship between humoral and local anti-sperm antibody production and infertility in turkey breeder hens
… effect upon hen fertility, or serum anti-sperm antibody titers. No differences in fertility were found between hens showing a positive or negative anti-sperm antibody response. Experiment II demonstrated that only relatively infertile turkey hens had antibody positive cells within the …
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Evaluation of hollow fiber bioreactors as an alternative to murine ascites production for small scale monoclonal antibody production
Thesis (M.S.)--Massachusetts Institute of Technology, Division of Toxicology, 1994.
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Nachweis von Antikörpern gegen Exophiala dermatitidis bei Patienten mit zystischer Fibrose
… A and C were revealed for IgG-, IgA and IgE-antibody production. In case of group A and B a significant difference was determined only for IgG-antibody production. In conclusion, the developed immunoassay proved to be well suited for serologic monitoring of colonized CF patients.
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Influence of body condition and homo- vs. heterosubtypic immunity on influenza A virus infection in mallard ducks : experimental infection data
… affects susceptibility, viral shedding, and antibody production in wild-caught and captive-bred juvenile mallards challenged with IAV H5N9. We found wild mallards fed <italic>ad libitum</italic> were more susceptible to IAV infection, shed higher virus loads, and shed virus more frequently …
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The Effects of Lead Acetate on Host Susceptibility to Trypanosoma Cruzi
… and viral infection causes decreases in antibody production, T cell recognition, and macrophage activity—all of which result in decreased host resistance to infection. The present study was conducted to determine the immunosuppressive effects of lead acetate in C57B1/6 mice challenged …
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The Development and Application of a Hemolytic Plaque Forming Cell Assay (PFC) and a Cytotoxic T-Lymphocyte Assay (CTL) in Tilapia (Oreochromis niloticus) for Immunotoxicity Risk Assessment of Environmental Contaminants
… (CTL) assays, quantitative indicators of antibody production and cell-mediated activity, respectively. The assays were modified in consideration of specific tilapian immune parameters, then tested using fourteen environmental contaminants or drugs, ten of which are classified by the NTP as …
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