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Showing 1 to 3 of 3 for “"Antibodies, Antinuclear"”.

  1. Common Alleles of the SLAM/CD2 Family are Associated with Murine Lupus

    … B6.Sle1b congenic mice produce anti-nuclear autoantibodies (ANAs), and have elevated activated B and CD4+ T cells, and mild splenomegaly. Fine mapping of Sle1b positioned it within a ~900 kb region between 171.3 and 172.2 Mb. A contig of 100 B6-derived Bacterial Artificial Chromosomes (BACs) was …

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  2. In Vivo Identification of SLE1B: LY108 Mediates Autoantibody Production

    In the NZM2410 model of murine lupus, Sle1b mediates anti-nuclear autoantibody (ANA) production. Our goal is to determine the causative gene in the Sle1b locus. Seven members of the SLAM/CD2 family are located within the Sle1b interval, and previous work has shown that structural and expression …

    utswmed Repository record for In Vivo Identification of SLE1B: LY108 Mediates Autoantibody Production (opens in a new tab)

  3. Are Antinuclear Antibodies and Rheumatiod Factor Positivity More Prevalent in Apparently Healthy Smokers Compared to Ex-Smokers and Never Smokers?

    … 1997; Silman, 1996; Uhlig, 1999; Wolfe, 2000). Antinuclear Antibodies (ANA) are another collection of autoantibodies that are being associated with smoking and RA initiation. To our knowledge, no studies have examined the effects of smoking on both ANA and RF simultaneously in healthy …

    loma-linda Repository record for Are Antinuclear Antibodies and Rheumatiod Factor Positivity More Prevalent in Apparently Healthy Smokers Compared to Ex-Smokers and Never Smokers? (opens in a new tab)