Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 98 for “"Antibiotic treatment"”.
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Bistability, Synthetic Biology, and Antibiotic Treatment
… with either synthetic gene circuits or antibiotics. A synthetic gene circuit is often engineered by considering the host cell as an invariable "chassis". Circuit activation, however, may modulate host physiology, which in turn can drastically impact circuit behavior. I illustrate this …
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Synergistic Effects of Monoculture Biofilm Dispersion and Antibiotic Treatment
… state, bacterial cells are less susceptible to antibiotic therapy. However, once released from a biofilm, antimicrobial susceptibility returns. In an aim to increase antibiotic efficacy of CAUTI treatment, uropathogenic Pseudomonas aeruginosa PAO1 and Escherichia coli F11 biofilms were cultured …
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The effect of antibiotic treatment on Haemophilus parasuis colonization, disease and immunity
… to investigate the influence of antimicrobial treatment on H. parasuis colonization and infection, and its effect on the development of immune responses against H. parasuis in swine. First, a species-specific ELISA assay and an experimental model of H. parasuis colonization were developed to …
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A mechanistic understanding of the postantibiotic effect and treatment strategies
<p>Although antibiotics have proven to be one of the great achievements of modern medicine, their efficacy has dramatically decreased over the past several decades. This is due, in part, to the rapid pace of natural bacterial evolution, but also to the overuse and misuse of antibiotics in general. …
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The use of antibiotics in the control of infertility in turkey populations
This study evaluated the effects of an antibiotic (oxytetracycline HCL) on reproductive performance of turkey breeder hens. The antibiotic was administered in 1) drinking water or 2) drinking water and intravaginal infusion. Hens were assigned to fertility subclasses (low 0-70%, medium 71-90%, high …
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Effects of subtherapeutic doses of antibiotics on poultry intestinal bacteria
… of the diet with low concentrations of antibiotics stimulates the growth of poultry by affecting the intestinal flora. The bacterial flora of the small intestine of turkey poults was extensively analyzed in an attempt to correlate changes in populations with growth response. …
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Approaches to investigating antibiotic efficacy and discovery of treatment strategies against antibiotic tolerance
While it is widely understood that antibiotic resistance is challenging the efficacy of our antibiotic therapies, there is a growing appreciation for the clinical importance of other ways that bacteria can survive antibiotic treatment. In particular, antibiotic tolerance describes a set of …
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Metagenomic Analysis of Antibiotic Resistance Genes in the Fecal Microbiome Following Therapeutic and Prophylactic Antibiotic Administration in Dairy Cows
The use of antibiotics in dairy cattle has the potential to stimulate the development and subsequent fecal dissemination of antibiotic resistance genes (ARGs) in bacteria. The objectives were to use metagenomic techniques to evaluate the effect of antibiotic treatment on ARG prevalence in the fecal …
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Antibiotic Stewardship Program Development in a Rural Urgent Care Clinic
Problem: The misuse and overuse of antibiotics are critical factors leading to antimicrobial resistance (AMR) and infections becoming harder to treat. Most antibiotics are prescribed in outpatient settings for upper respiratory infections (URIs), yet these infections are commonly caused by viruses …
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Effect of Composting on the Prevalence of Antibiotic Resistant Bacteria and Resistance Genes in Cattle Manure
Antibiotic resistance is a growing human health threat, making infections more difficult to treat and increasing fatalities from and cost of treatment of associated diseases. The rise of multidrug resistant pathogens threatens a return to the pre-antibiotic era where even the most common infections …
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Lumbar punctures in the paediatric emergency medicine department at Red Cross War Memorial Children's Hospital: An evaluation
… prolong hospital stay and result in unnecessary antibiotic treatment and increased costs to the hospital and patients. It is important to determine factors that may be effective in reducing unsuccessful LPs. There is a paucity of studies on this topic from sub-Saharan Africa. Previous studies …
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Immune Checkpoint Blockade Induces Gut Microbiota Translocation That Augments Extraintestinal Anti-Tumor Immunity
… lymph nodes (TDLN) and the primary tumor. Antibiotic treatment results in decreased gut microbiota translocation into MLN and TDLN, diminished DC and effector CD8+ T cell responses, and attenuated response to ICT. Our findings illuminate a key mechanism by which gut microbiota promote …
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Isolation and Characterization of Anti-SLP Single Domain Antibodies for the Therapy of C. difficile Infection
… infections in Canada. Current antiobiotic treatment is non-ideal due to the high incidence of relapse and the rise in hyper-virulent antibiotic-resistant strains. Surface layer proteins (SLPs) cover the entire bacterial surface and mediate adherence to host cells. Passive and active …
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From genomes to metagenomes: Big data analysis of microbes related to public health
… is largely driven by selection pressures (e.g., antibiotic treatment). Therefore, these findings advance our knowledge on the diversity and dynamics of microbial communities and their potential links to public health.
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Midline Catheter Usage in the Neonatal Population
… and susceptibility to sepsis make them prone to antibiotic treatment. Lack of recommendations points to the need for evidence-based practices when selecting a vascular access device (VAD). Literature reviewed demonstrated that a midline catheter (MC) was an option for a VAD with neonatal …
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Genetic mechanisms contributing to antimicrobial resistance: gene repression in Mycobacterium, gene transfer in Salmonella, and phage sensitivity in Escherichia
… increasing resistance to conventional antibiotic treatment. Understanding the genetic mechanisms that regulate antibiotic resistance are critical in developing new antimicrobials and improving current treatment regimens. Alternative therapies to antibiotics should also be considered in …
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Computational prediction of health status from the human gut microbiome and metabolome
… after the microbiome is disrupted, such as by antibiotic treatment. However, because the microbiome is so diverse and individual-specific, very little is known about the specific microbial changes that may lead to human disease. Thus, it is extremely difficult to predict whether a given …
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HAEMOPHILUS INFLUENZAE AND MORAXELLA CATARRHALIS INTRA- AND INTERSPECIES QUORUM SIGNALING
… periods of time and can be highly resistant to antibiotic treatment due in part to persistence of bacteria within biofilms. The majority of OM infections also involve coinfection by multiple species. For instance, the leading causative agents <italic>Haemophilus influenzae</italic> and …
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Changes in the Oral Cavity and Common Diseases /// Промени в оралната среда и общи заболявания
… in saliva reveals a decrease in values after antibiotic treatment and outlines a new marker for monitoring patients with periodontal problems. Half of Bulgarian patients have dental amalgam. The greatest amount of mercury is released throughout polishing and removal of old fillings. 30% of …
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Effects And Interactions Of Antibiotic, Butyrate, And Temperature On Sailfin Molly (Poecilia Latipinna) Metabolism And Gut Microbiota
… settings. This study examines the effects of antibiotic, butyrate, and temperature treatments on the metabolism and gut microbiota of sailfin molly (Poecilia latipinna) alone and in combination. The results indicate that butyrate successfully restored the growth rates due to antibiotic …
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