Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 70 for “"Antibiotic resistant bacteria"”.
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The relevance of bacteriophage therapy in the era of antibiotic resistant bacteria
Against a backdrop of rising antibiotic resistance and a dwindling pipeline of new antibacterial drugs, this thesis set out to examine the potential of bacteriophage (phage) therapy as an alternative or complementary means of treating bacterial infection. Phage therapy is used as a frontline …
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An assessment of antibiotic resistant bacteria in biosolid used as garden fertilizer
… from the Cheney Wastewater Treatment Plant and antibiotic resistant gram negative bacteria were isolated from it. Bacteria isolated from these samples were resistant to tetracycline, ampicillin, streptomycin, kanamycin and chloramphenicol. Tetracycline resistant bacteria were isolated on …
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Investigation of the prevalence of antibiotic resistant bacteria and their genes in wastewater
Antibiotics are therapeutic agents commonly used in the treatment of infections caused by microorganisms. Due to the increased demand of antibiotics, they have become environmental pollutant to both water and soil. This have caused adverse effects to human, animals, aquatic ecosystem and in the …
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Molecular Profiling of Antibiotic Resistant Bacteria and Genes in Raw and Drinking Water
Antibiotic resistant bacteria and antibiotic resistant determinants are regarded as emerging public health threats in drinking water systems. Heterotrophic Plate Count bacteria in distribution pipes are used as direct parameters to assess the conditions of water in distribution systems. Moreover, …
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Effect of Composting on the Prevalence of Antibiotic Resistant Bacteria and Resistance Genes in Cattle Manure
Antibiotic resistance is a growing human health threat, making infections more difficult to treat and increasing fatalities from and cost of treatment of associated diseases. The rise of multidrug resistant pathogens threatens a return to the pre-antibiotic era where even the most common infections …
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Effect of Standard Post-harvest Interventions on the Survival and Regrowth of Antibiotic-Resistant Bacteria on Fresh Produce
… for fresh vegetables to serve as a vehicle for antibiotic -resistant bacteria is poorly understood. Antibiotics and antibiotic-resistant bacteria have been shown to persist in manure of animals administered antibiotics, and in compost generated from this manure, where there is the potential for …
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Fate and transport of antibiotic resistant bacteria and resistance genes in artificially drained agricultural fields receiving swine manure application
… led to increasing concerns regarding levels of antibiotics and antibiotic resistant bacteria in their excrement. Application of swine manure to agricultural fields as fertilizer creates a pathway for antibiotic resistant bacteria and their associated resistance genes to enter the environment. …
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Effect of Soil Amendments from Antibiotic Treated Cows on Antibiotic Resistant Bacteria and Genes Recovered from the Surfaces of Lettuce and Radishes: Field Study
Cattle are commonly treated with antibiotics that may survive digestion and promote antibiotic resistance when manure or composted manure is used as a soil amendment for crop production. This study was conducted to determine the effects of antibiotic administration and soil amendment practices on …
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Antibiotic Resistance Genes in Marquette County Michigan's Wastewater
<p>Antibiotic-resistant bacteria evade standard treatments, increasing disease severity, patient morbidity, and mortality. Following exposure to an antibiotic, resistant bacteria survive and pass antibiotic resistance genes (ARGs) to their progeny cells. Few ARG studies have utilized wastewater …
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TESTING THE EFFECT OF A NOVEL HYDROGEN SULFIDE RELEASING PEPTIDE ON INFECTED BURN WOUNDS
… at least 2 million people are diagnosed with antibiotic-resistant bacteria, and more than 20,000 people die as a result.
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Combating biofilms and antibiotic resistance using synthetic biology
Bacterial infections represent a significant source of morbidity and mortality. Biofilms and antibiotic resistance pose challenges to our future ability to treat bacterial diseases with antibiotics (1). Bacteria frequently live in biofilms, which are surface-associated communities encased in a …
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Controlling bacterial contaminants in sugarcane ethanol fermentations
… species and other lactic acid producing bacteria from the feedstock and environment are important bacterial contaminants. Further studies focused on process optimization and validated the use of antibiotics and acid treatment to reduce ethanol losses due to bacterial contamination. …
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TARGETING MULTI-DRUG RESISTANT PATHOGENS WITH NOVEL ANTIMICROBIAL PEPTIDES
The emergence of antibiotic resistance is a notorious problem worldwide. In the United States alone, antibiotic-resistant bacteria infect at least two million people and kill around 23,000 patients each year. Half of these infections are attributed to the bacterial pathogen, methicillin resistant …
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A Mathematical Model for Antibiotic Resistance in a Hospital Setting with a Varying Population
<p>Antibiotic-resistant bacteria(ARB) is causing increased health risk and cost to society. Mathematical models have been developed to study the transmission of resistant bacteria and the efficacy of preventive measures to slow its spread within a hospital setting. The majority of these models have …
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Cooperative behaviors in the evolution of antibiotic resistance
… and modeling, I explored how inactivation of antibiotics by antibiotic-resistant bacteria affects the evolution of antibiotic resistance in two simple microbial communities. First, I examined the interaction between a resistant strain and a sensitive strain of the bacteria Escherichia coli in …
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Herbicide Mediated Selection of Sulfonamide Resistant E. coli
… that is structurally analogous to sulfonamide antibiotics (sulfas), with the potential to contribute to the global antibiotic resistance crisis by cross-selecting for sulfa-resistant bacteria. To determine if asulam can select for antibiotic resistant bacteria, isothermal titration calorimetry …
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An evaluation of co-culture parameters effecting antibiotic production in soil microbes
<p>The rise of infections caused by antibiotic resistant bacteria, compounded by a reduction in antibiotic discovery and development, jeopardizes human health. Historically, antibiotics derive from secondary metabolites produced by soil microbes in pure culture, but recent genetic evidence suggests …
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Investigating the role of phosphate homeostasis in Staphylococcus aureus virulence
… is an essential nutrient for all organisms. Bacteria possess a variety of complex phosphate sensing and uptake systems to ensure that they meet their need for phosphate. The ubiquity and necessity of these systems make them a possible target for novel therapeutics to treat …
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Engineering membrane-selective antibiotic peptides to combat multidrug resistance
Antibiotic resistance is a global health emergency that mandates new drug development strategies. Natural antimicrobial peptides (AMPs) have been long-recognized as a potential source of bacteriolytic drugs, but the shortcomings of non-specific membrane toxicity, proteolytic instability, and in …
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