Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Antibiotic efflux"”.
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Characterisation of bedaquiline resistance mediated by the <i>M. tuberculosis</i> MmpS5L5 efflux pump
… drug-resistant tuberculosis required prolonged antibiotic treatment, often up to two years, with a toxic combination of less effective drugs. Bedaquiline, an antibiotic that targets the mycobacterial ATP synthase, has revitalised the ability to treat multidrug-resistant tuberculosis as part of …
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Structure & Function of Bacterial Transport Machines in their Cellular Context
… species are the MacA-MacB-TolC (MacAB-TolC) antibiotic efflux pump and the Type I Secretion System (T1SS), responsible respectively for antibiotic resistance and export of protein virulence factors. To pass the Gram-negative envelope in a one-step translocation process, both machines use a …