Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"Antibiofilm"”.
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A Novel Antibiofilm Treatment for Surgical Site Infections
… biofilms. In this thesis, the antibacterial and antibiofilm activities of DDC- with Cu2+ were examined and an injectable gel containing the combination was developed for application on SSIs. The antibacterial and antibiofilm activity of DDC- was strictly Cu2+-dependent and linked to the formation …
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INVESTIGATION OF ANTIBIOFILM AND ANTIVIRULENCE ACTIVITY OF 5-FLUOROCYTOSINE IN ESCHERICHIA COLI
… and my results proved that it possesses potent antibiofilm activity compared to other fluoropyrimidines, I focused on this molecule in further experiments. I tried to elucidate the molecular mechanisms behind the antibiofilm activity of 5-FC in E. coli and observed that curli inhibition by 5-FC …
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Antibiofilm properties of selected Lactobacillus species and their mechanism of action against Listeria monocytogenes
… certain probiotic properties as an alternative antibiofilm agent. Research has highlighted that the use of substances produced by LAB achieves inhibition and dispersal of L. monocytogenes biofilms. The antimicrobial substances of LAB have been revealed to showcase antilisterial activity, …
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Antioxidant, Antimicrobial, and Antibiofilm properties of Opuntia stricta and Vachellia erioloba, and chemical characterization of volatile compounds
… to investigate the antioxidant, antimicrobial, antibiofilm activity, and chemical characterization of V. erioloba and O. stricta. The radical scavenging capacity of extracts was estimated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and the reducing power was determined using ferric reducing power …
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Identification of potential antibiofilm hit compounds from two African natural product database against multi-drug resistant staphylococcus aureus: an in silico study
… This study seeks to identify effective potential antibiofilm compounds from a query dataset compiled from two African natural product databases (SANCDb and AfroDb). A database of known antibiofilm compounds was created from ChEMBL, PubChem, and other related databases while a query dataset of …
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Controlling Microbial Multicellular Behaviors With Saccharide Derivatives
… ones (antibiotics). This study describes a new antibiofilm approach of using nonmicrobicidal saccharide derivatives for controlling the multicellular behaviors of gram-negative bacteria, Pseudomonas aeruginosa and fungus, Candida albicans.</p> <p>Pseudomonas aeruginosa is known to secrete …
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Molecular cloning, structural characterisation and functional study of peptides from amphibian skin secretion
… In addition, the antimicrobial activity and antibiofilm activity of AMPs were assessed and their haemolysis activity was also tested. Apart from these, the relationship between structure and function of AMPs was determined by means of CD experiments and secondary structure predictions. …
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Use of electromagnetic stimulation on an Enterococcus faecalis biofilm in root canal treated teeth in vitro
… cannot be rejected. However, there was an antibiofilm effect when comparing the two saline groups, demonstrating that EMS has an antibiofilm effect. Future studies should focus on determining what concentration of NaOCl is most effective in combination with EMS.
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The membrane-active antimicrobial peptide from frog skin and scorpion venom: from mechanistic insight to design
… brevinin-1GHd exhibited potent antimicrobial, antibiofilm, and anticancer efficacy without inducing obvious haemolysis and cytotoxicity at working concentrations, which made it promising to be further developed as an alternative novel antibiotic agent or used as a template to design some …
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Towards a more efficacious treatment for Oropharyngeal Candidiasis (OPC): Hydrogel-forming tablets for the controlled release delivery of Chlorhexidine diacetate
… thymol to 250 and >250 μg/ml, respectively. The antibiofilm activity of CHD and thymol was concentration dependent and CHD was more potent than thymol. A concentration of 20 μg/ml and 2 hours treatment of Candida biofilm grown for 24 hours showed an 85% decrease in oxidative stress, 78% and 60% …
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Investigation of novel topical therapeutics for chronic rhinosinusitis
… most likely to offer the best balance between antibiofilm efficacy and sinonasal toxicity. Tofacitinib suppresses the transcription of target genes of cytokine receptor activation relevant to CRS. Tetracaine 2% with oxymetazoline 0.05% produced more rapidly acting and potent anaesthesia than …
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Evaluation of the antimicrobial activity of Plectranthus amboinicus leaf extracts on planktonic and biofilm forms of Staphylococcus aureus and Pseudomonas aeruginosa
… were evaluated for their antimicrobial and antibiofilm activity on Pseudomonas aeruginosa PA01 (Gram-negative pathogen) and Staphylococcus aureus NCTC8325 (Gram-positive pathogen). Extracts from the log phase exhibited the highest concentration of bioactive compounds, with the lowest minimum …
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Investigating physiological and genetic characteristics of community acquired infections and potential antimicrobial interventions
… EO was effective as an antibacterial and antibiofilm agent and could be a potential alternative to chemical based antimicrobial agents in both healthcare and non-healthcare environments.
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Investigation of biofilm development by antibiotic resistant urinary tract infection pathogens and evaluation of antimicrobial activity of Manuka honey on Escherichia coli CTX-M-15 biofilms
… Manuka honey had powerful antibacterial and antibiofilm abilities and can be considered a reliable alternative therapy.
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A drug-free theranostic approach for localized and systemic diseases via nanoparticles
… toward carious bacteria. The therapeutic antibiofilm properties of these nanoparticles were established as well by comprehensive in vitro and in vivo studies. The inherently therapeutic nanoparticles of carbon which target the pH of the biofilm were investigated in the follow-up study …
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Discovering the Biological Activities of Maltose Derivatives for Controlling Bacterial Multicellular Behaviors
… SdiA of E. coli was found to be critical for antibiofilm activities of brominated furanones against E. coli. The lasI protein on P. aeruginosa is a known homologue of the E. coli SdiA protein. It was found that the brominated furanones were antagonistic to the las QS system but were agonistic …
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Antimicrobial and antioxidant active packaging incorporated with hop (Humulus lupulus L.) extract: development, characterization and application in meat product
… antimicrobial, quorum quenching, and antibiofilm properties) and in situ (test with a bologna real food system) bioactivity. This work confirmed the potential of inclusion complexation with cyclodextrins as carriers for hop β-acids and application in active packaging development. In …
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Studio delle caratteristiche nutraceutiche e salutistiche degli oli di oliva extravergine e delle olive da tavola CV Tonda di Cagliari, possibile utilizzo di comuni cibi da tavola nella modulazione del microbioma orale umano
… thesis it were evaluated the antimicrobial and antibiofilm effects of some common foods typical of the Mediterranean diet (Allium sativum L .; Allium cepa L .; Ocimum basilicum, L .; Petroselinum crispum) and shiitake mushroom (Lentinula edodes) extracts. Actually this is an important topic of …
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Photodynamic therapy against multidrug-resistant oral strains of Candida spp
… by Kirby Bauer; (ii) growth curve inhibition and antibiofilm activity through the microplate dilution method; (iii) activity of PDT against a subprosthetic in vitro C. glabrata infection. For these in vitro procedures, a large set of commercial and natural PT as well as different light sources …
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in vitro studie van Candida albicans en Streptococcus mutans biofilms
… under different conditions and to evaluate antibiofilm strategies. The densest biofilms were achieved in the CDC biofilm reactor, which is well suited for monitoring biofilm growth kinetically. The golden standard for quantifying biofilm biomass is plating, although complete detachment of …
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