Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 26 for “"Anti-retroviral therapy (ART)"”.
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Effects of HIV and different anti-retroviral therapy (ART) regimes on brain structure in HIV infected children at age 7
… Organization (WHO) recommended early aggressive antiretroviral therapy (ART) initiation to manage HIV in children, based on studies that reported this protocol as effective in reducing mortality and HIV progression. Early ART initiation in HIV-infected children generated new concern about the …
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Radiological progression of lung disease in Human Immunodeficiency Virus (HIV)-infected children
… of HIV-disease, and to assess the impact of anti-retroviral therapy (ART). Method: A prospective longitudinal study evaluating clinical, immunological and radiographic parameters at regular intervals over a minimum of 24 months. CXR abnormalities were stratified by severity and deemed …
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Probabilistic Population Projection for Countries with Generalized HIV/AIDS Epidemics
… HIV impact, including HIV prevalence and anti-retroviral therapy (ART) coverage in projecting life expectancy and age- and sex-specific mortality, and use them to probabilistically project population for countries with generalized HIV/AIDS epidemics. Through out-of-sample validation, we …
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Analysis of retention incare among HIV patients in selected health care facilities in Zambia 2013-2015
… 2015). Despite significant success in scaling up Anti-retroviral Therapy (ART) programmes worldwide, many people living with HIV (PLHIV) start ART late in the progression of HIV infection, resulting in high rates of early mortality on ART. Poor retention of patients in care – especially in ART is …
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Analysis of retention incare among HIV patients in selected health care facilities in Zambia 2013-2015
… 2015). Despite significant success in scaling up Anti-retroviral Therapy (ART) programmes worldwide, many people living with HIV (PLHIV) start ART late in the progression of HIV infection, resulting in high rates of early mortality on ART. Poor retention of patients in care – especially in ART is …
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Modulation of Host BRD4 to Repress HIV Replication in Myeloid Cells: Major HIV Reservoirs in Central Nervous System
… in central nerve system (CNS). Despite anti-retroviral therapy (ART), low-level persistent HIV replication in these reservoirs remains detectable, which contributes to neuroinflammation and neurological disorders in HIV-infected patients. New approaches complimentary to ART to repressing …
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The influence of traditional healing practices on anti-retroviral treatment adherence in Vhembe District, South Africa
… influence of traditional healing practices on anti-retroviral treatment adherence in Vhembe District. This qualitative study used an explorative design to envisage the aim. A cross-sectional snowball sample was used to draw a sample of 9 participants from the 4 municipalities of Vhembe …
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Factors associated with adherence to anti-retroviral therapy in Katima Mulilo hospital, Namibia
… orphans due to the disease. The introduction of anti-retroviral therapy (ART) in public health facilities in Namibia in 2003 has improved the quality of lives of patients with advanced HIV disease, prolonged their lives and enabled them to be economically productive. By 2010 about 90,000 patients …
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Longitudinal study to assess the prevalence of hypogonadism in HIV-infected South African men and its association with bone density, body composition, metabolic abnormalities (dysglycaemia, dyslipidaemia) and quality of life.
… described in association with HIV infection and anti-retroviral therapy (ART). Furthermore, hypogonadism is associated with comorbidity and a reduced quality of life. The prevalence of hypogonadism in HIVinfected South African men is unknown. We examined the prevalence of hypogonadism in …
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Factors affecting antiretroviral drug adherence among HIV adult patients attending HIV clinic at the university teaching hospital in Lusaka.
1.0 Abstract Introduction The effectiveness of anti-retroviral therapy (ART) relies on a strict adherence to it. To achieve optimum therapeutic levels and reduce drug resistance requires levels ≥95% adherence. As such, identifying factors to adherence is essential. We sought to determine factors …
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Associatioin of severe anaemia with tuberculosis mycobacteraemia in HIV positive patients admitted with severe sepsis to the University Teaching Hospital, Lusaka,Zambia
… data from 2 patients enrolled independently. Participants were adults who met the inclusion criteria for severe sepsis. Baseline data was collected on demographic and laboratory characteristics including blood cultures for tuberculosis and aerobic organisms. RESULTS: The prevalence of …
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Association of severe anaemia with tuberculosis mycobacteraemia in HIV positive patients admitted with severe sepsis to the University Teaching Hospital, Lusaka,Zambia
… data from 2 patients enrolled independently. Participants were adults who met the inclusion criteria for severe sepsis. Baseline data was collected on demographic and laboratory characteristics including blood cultures for tuberculosis and aerobic organisms. RESULTS: The prevalence of …
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Associatioin of severe anaemia with tuberculosis mycobacteraemia in HIV positive patients admitted with severe sepsis to the University Teaching Hospital, Lusaka,Zambia
… data from 2 patients enrolled independently. Participants were adults who met the inclusion criteria for severe sepsis. Baseline data was collected on demographic and laboratory characteristics including blood cultures for tuberculosis and aerobic organisms. RESULTS: The prevalence of …
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An exploratory study of perceived barriers to antiretroviral therapy adherence amongst adolescents in Omuthiya district, Namibia
… sought to explore the perceived barriers to Anti-Retroviral Therapy (ART) adherence amongst adolescents in Omuthiya District, Namibia. Omuthiya was selected because it was where the researcher resides so they identified the problem among the Omuthiya vicinity and therefore this study is a way …
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Sam68, Stress Granules, and translational control of HIV-1 nef mRNA
… 34 millions are currently infected with the HIV. Anti-retroviral therapy (ART) directed at key viral enzymes has changed AIDS from uniformly fatal to a manageable chronic disease. However, ART-associated drug resistance and toxicity have posed a great challenge for long-term management of the …
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Assessing the Efficacy of Interleukin-7 as an Immunotherapeutic in the SIV+ Rhesus Macaque Model
… depleting ‘helper’ CD4+ T cells. Highly active antiretroviral therapy (HAART) reduces viremia and increases CD4+ levels, however, 5-20% of patients fail to reconstitute CD4+ T cell levels despite viral suppression. Interluekin-7 (IL-7), a homeostatic cytokine, increases proliferation and …
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HIV-associated Neuropathy and Autonomic Dysfunction in South Africans on established ART impacts daily living
… of Human Immunodeficiency Virus (HIV) and anti-retroviral therapy (ART) is distal sensory polyneuropathy (DSP). Older age and previous TB are risk factors for DSP among HIVinfected Africans before and shortly after ART initiation. Little is known about autonomic dysfunction in Africans on …
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Investigating the susceptibility of foreskin myeloid cells to ex vivo HIV infection
… a global concern that, although manageable using anti-retroviral therapy (ART), is still eluded by a cure with paucity of knowledge regarding its acquisition and spread especially through the male genital tract (MGT)1–4. Several authors have shown the human foreskin to be an effective mucosal …
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Enhancing T-Cell Responses to Vaccination of HIV-1 infected Subjects on Antiretroviral Therapy
With the advancement in anti-retroviral therapy (ART) regimens there has been a significant improvement in the quality of life and survival of those individuals infected with HIV-1. Even with the benefits to CD4+ cell counts, decrease in viremia and inflammatory biomarkers, HIV-1 infected …
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The effects of lipid-based nutrient supplements containing vitamins and minerals on renal excretion of electrolyte and tenofovir concentrations in blood among Zambian HIV/AIDS patients
… HIV-infection combined with under-nutrition and anti-retroviral therapy (ART) places patients at high risk of electrolyte abnormalities and/or losses as well as increased mortality. Aims: This study evaluated if nutritional supplements would help curtail renal electrolyte loss and determined …
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