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Showing 1 to 3 of 3 for “"Anti-repressor"”.

  1. Regulation of the mobile genetic element ICEBs1 by a conserved repressor and anti-repressor

    … and transfer by inactivating the ICEBsl repressor protein ImmR. Although ImmR is similar to many characterized phage repressors, we found that, unlike these repressors, inactivation of ImmR requires an ICEBslencoded anti-repressor ImmA (YdcM). Under ICEBsl-inducing conditions, ImmA …

    mit Repository record for Regulation of the mobile genetic element ICEBs1 by a conserved repressor and anti-repressor (opens in a new tab)

  2. Synthetic Transcription Factor Allostery Mapping and Analysis

    … correlations from engineered LacI-based anti-repressors. Through deep mutational scanning, we have generated comprehensive datasets correlating single-mutant genotypes with functional phenotypes. Building upon the experimental dataset and alongside ongoing machine learning efforts that …

    gatech Repository record for Synthetic Transcription Factor Allostery Mapping and Analysis (opens in a new tab)

  3. Engineering Novel Bandpass Tools for Cascading Gene Expression

    … gates for cascaded gene expression, where each repressor-anti-repressor pair is directed to regulate the expression of a single gene. To achieve this fusion, a series of foundational logic operations were built and tested. These included single-input single-output (SISO) logic operations and …

    gatech Repository record for Engineering Novel Bandpass Tools for Cascading Gene Expression (opens in a new tab)