Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 61 for “"Anti-inflammatory activity"”.
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Investigating the Anti-inflammatory Activity of Honey
… standardisation. This thesis focuses on the anti-inflammatory activity of honey. Emphasis was put on identifying the mode of action of the anti-inflammatory component, creating an in vitro assay to measure the anti-inflammatory activity of individual honeys and attempting to identify and …
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Natural products from the olive tree with anti-inflammatory activity
Η χρόνια φλεγμονή αναγνωρίζεται ως κεντρικός μηχανισμός στην παθογένεση των κυριότερων μη μεταδοτικών νοσημάτων, όπως τα καρδιαγγειακά νοσήματα, ο καρκίνος, το μεταβολικό σύνδρομο και οι νευροεκφυλιστικές διαταραχές. Η παρούσα εργασία διερευνά τις αντιφλεγμονώδεις ιδιότητες των βιοδραστικών ενώσεων …
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Contribution to the elucidation of the anti-inflammatory activity of Sesquiterpene Lactones
… in p50. <br>A densitometric method for the quantification of EMSA analyses was also established. This allowed the determination of the concentration required to obtain a half-maximal inhibition of NF-kB (IC50). The method was used to calculate the IC50 values for 24 SLs. <br>Up to now, the …
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IN VITRO LUNG EPITHELIAL CELL TRANSPORT AND ANTI-INFLAMMATORY ACTIVITY FOR LIPOSOMAL CIPROFLOXACIN
… with a goal of sustaining the therapeutic activity, compared to unformulated ciprofloxacin (CPFX). However, the kinetics and mechanism of its sustained local lung retention and pharmacological activity are yet to be fully characterized. This project hypothesized that Lipo-CPFX enables …
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Pharmacologic investigation of the anti-inflammatory activity of cryogenine and selected benzoquinolizine derivatives
… many centrally active agents possess potential anti-inflammatory capabilities. The central or peripheral mechanisms of action for these agents have not been delineated nor has their clinical efficacy baan established or refuted. The centrally active drugs, cryogenine and tetrabenazine (a …
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Antithrombotic and anti-inflammatory activity of ethyl acetate extract of Protorhus longifolia stem bark
… Despite great efforts made in the discovery of antithrombotic agents, ischemic events continue to claim more lives. Thus, there is a need to discover and develop new and more effective antithrombotic drugs, preferably from natural sources. The study is aimed at investigating the anti-thrombotic …
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Characterization of Molecular Content, Cytotoxicity, and Anti-Inflammatory Activity of Extractions from Eupatorium serotinum
… montana</em> have been studied for their anti-inflammatory properties. In this study, we identified and harvested samples of <em>Eupatorium serotinum</em>, a plant historically used by Native Americans to treat a variety of medical illnesses. Crude extracts of the leaves, flowers, roots, …
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Activities of extracts and constituents of two Libyan ornamental plants relevant to anti-inflammatory activity
Strathclyde theses - ask staff. Thesis no. : T12804
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The vascular and anti-inflammatory activity of Cyanidin-3-Glucoside and its metabolites in human vascular endothelial cells
… for their reported health effects; yet the bioactivity of anthocyanin metabolites remains largely unknown. This thesis aimed to address this deficiency in current scientific literature by investigating the vascular and anti-inflammatory activity of cyanidin-3-glucoside (C3G), the most abundant …
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Anti-oxidant Action and Anti-aging Activity of Phenylpropanoid Compounds
… relationship between structure and biological activity of phenylpropanoids, we measured effects of phenylpropanoids on anti-oxidant and anti-inflammatory activity and effect of caffeic acid on wound healing in skin-incised mice. Materials & methods: The cinnamic acid derivaties, C_(6)-C₃ …
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I. Estrogen receptor-mediated inhibition of inflammatory signaling: Implications for treatment of breast cancer II. Small molecule coactivator-binding inhibitors
… this resistance. In Chapter 2, the unique anti-proliferative and anti-inflammatory activity of a lead compound, OBHS, is described. A crystal structure of OBHS bound to the estrogen receptor provided the basis for structural and functional analogs of OBHS. These compounds exhibited weaker …
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Development of dry powder Inhaler and nebulised nanoparticles formulations of chrysin for the potential treatment of asthma. Development of dry powder inhaler of chrysin and nebulised nanoemulsion combination of chrysin and budesonide; Evaluating the anti-inflammatory activity of the combination formulation of chrysin and budesonide for asthma
… chronic obstructive pulmonary disease due to its anti-inflammatory activities. However, no studies have investigated the effectiveness of an inhaled formulation of chrysin on its own or in combination with corticosteroids. Therefore, this study aimed to assess the aerosol performance of chrysin …
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Investigating the therapeutic effects of silver and gold nano particles capped with selected medicinal plants against tuberculosis
… mass spectrometry (LC-MS). Cytotoxicity activity of plant extracts and nanoparticles were determined by MTS assay on HEK293 cells. The anti-inflammatory activity was determined through the nitric acid synthase (NOS) inhibitory test. The antimycobacterial activity was determined using …
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The antioxidant activity of Bulgarian medicinal plants // Проучване на антиоксидантната активност на български лечебни растения
[EN] In vitro antioxidant activity of extracts and fractions from 54 medicinal plants with application in Bulgarian traditional medicine is the subject of this study. By analysis of the results obtained, one plant was chosen to examine its extract antioxidant and anti-inflammatory activity in …
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Isolation and Synthesis of Bioactive Compounds from Plants
… plant extracts were investigated for their antiproliferative activity against the A2780 cell line, three plant extracts were investigated for their antimalarial activity against Plasmodium falciparum, and three plant extracts were investigated for their anti-inflammatory activity (PPAR-y …
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Evaluation of the antioxidant activity of extracts and flavonol glycosides isolated from the seed coats of coloured beans (Phaseolus vulgaris L.)
… Therefore, a better understanding of the antioxidant and anti-inflammatory activity of coloured dry bean seed coats would be beneficial in determining their potential use as an ingredient in the functional food and nutraceutical industry. Flavonol glycosides were identified from acetone …
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Hematologic effects of cryogenine and certain selected anti-inflammatory agents
… (whether caused by micro-organisms, toxins, antigens, etc.) first leads to an increased passage of fluid through the walls of the microvasculature, followed by stasis of circulation within the affected area. This, in turn, is followed by migration of leukocytes into the area and finally …
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Particalized Eggshell Membrane (PEM) for Biomedical Applications
… range. PEM exhibited dose- and size-dependent antimicrobial activity against Gram-positive Staphylococcus aureus (S. aureus), and Gram-negative Pseudomonas aeruginosa (P. aeruginosa) and Escherichia coli (E. coli) species. A dose-dependent anti-inflammatory activity for PEM was observed in an …
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Neural stem cells respond to extracellular succinate via SUCNR1/GPR91 to ameliorate chronic neuroinflammation
… and secondary CNS damage. Mechanistically, the anti-inflammatory activity of NSCs arises in response to succinate released by inflammatory MPs, which activates succinate receptor 1 (SUCNR1)/GPR91 on NSCs, thus initiating prostaglandin E2 secretion and extracellular succinate scavenging. This …
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The Effect of Phosphodiesterase Inhibitors on the Induction of Gene Expression by Long-Acting beta2-Adrenoceptor Agonists and Glucocorticoids
… have received approval as a complementary anti-inflammatory treatment for chronic obstructive pulmonary disease (COPD) patients who are already taking long-acting β2-agonists (LABA)/inhaled corticosteroid (ICS) combination therapy. However, this benefit is seen only in patients of the …
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