Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 31 for “"Anti-inflammation"”.
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Antioxidant studies of fullerene and metallofullerene derivatives and fluorescence studies of terbium-containing metallofullerene derivatives
… area, for instance, they have been shown to have antioxidant, anti-virus, anti-cancer, immunological properties, etc. However, the hydrophobicity nature of fullerenes and metallofullerenes raises the need for functionalized hydrophilic fullerenes and metallofullerenes. Also, the advancement of the …
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Characterization of Mycochemicals and Bioactivities of a New Zealand Native Mushroom Hericium novae-zealandiae
… method was subsequently applied for the quantification of the identified compounds. In addition, the bioactivities of the extracts and the compounds were evaluated in relation to anti-proliferation of three prostate cancer (PCa) cell lines (DU145, LNCaP, and PC3), AChE inhibition and …
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Anticonvulsant effects of PPAR-gamma activation in an in vitro model of seizure
… insulin homeostasis, neuroprotection and anti-inflammation. As such, PPARγ is under consideration as therapy for ischemic stroke, Alzheimer's disease, Parkinson's disease, multiple sclerosis and traumatic brain injury. Previous in vivo experiments using acute seizure models and preliminary …
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Uncovering the hidden mechanisms governing the transcriptional regulation of inflammation
Inflammation provides broad immunological protection that is essential for our survival. This cellular response is characterised by a biphasic cycle consisting of an initial acute pro-inflammatory phase and a subsequent resolving anti-inflammatory phase. Underlying each of these phases are changes …
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The Role of Wnt3a in Ischemic Stroke
… investigated in the phenomena of neurogenesis, anti-apoptosis, and anti-inflammation, it has never been investigated as a therapy for stroke. We hypothesized that the potential neuroprotective agent wnt3a would reduce infarction and improve behavior following ischemic stroke by attenuating …
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Anti-inflammatory effect according to the maturity of Kimchi in obese patients
… of Kimchi on obesity, lipid metabolism, and anti-inflammation according to the maturity of Kimchi that was studied in obese patients. MATERIALS AND METHODS: Twenty-two obese patients, who’s BMI (basal metabolic index) was over 25 ㎏/㎡, did not have any fermented food including Kimchi for 2 …
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RNA-binding proteins mediate anti-inflammatory regulation of vascular disease
… is increased in VSMC challenged with the anti-inflammatory cytokine IL-19, and FXR1 is required for IL-19 reduction of HuR. This suggests FXR1 is an anti-inflammation responsive, HuR counter-regulatory protein that reduces abundance of pro-inflammatory transcripts. Additionally, we …
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Comparison of dose-dependent outcomes in induction of cytogenotoxic responses by novel glucosyl flavonoids
… with potential health-promoting effects such as anti-inflammation, anti-viral, anti-carcinogenesis, neuro- and cardio-protection, etc. Semi-synthetic water soluble quercetin glucosides, maltooligosyl isoquercetin (MI), monoglucosyl rutin (MO) and maltooligosyl rutin (MA) were developed to …
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Anti-VEGF Therapy Modulates Immune Cell Infiltration and Function in Multiple Breast Cancer Models
… target for tumor therapy. Many of the current anti-angiogenic therapies target vascular endothelial growth factor-A (VEGF). VEGF binds to and activates two primary VEGF receptors, VEGFR1 and VEGFR2. VEGFR2 is the primary angiogenic receptor, while the function of VEGFR1 is less defined. It is …
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Nano-engineered polymers in drug delivery: Potential approaches for attenuation of secondary injury after spinal cord trauma
… drug cargo, since this drug is commonly used for anti-inflammation treatment and has been successfully delivered from polypyrrole using conventional electrical stimulation methods in earlier studies. According to the results, we showed successful and long lasting polypyrrole mediated drug release …
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Berries in Prevention of Metabolic Disease – focus on obesity, diabetes and gut microbiota
… body weight gain, insulin resistance, low-grade inflammation and hepatic lipid accumulation in C57BL/6J mice fed a high-fat diet. Supplementation with raspberries, crowberries, blackberries or prunes had no or small effects, whereas açai berries promoted development of obesity and fatty liver …
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Interleukin-1 (IL-1) as a potential contributor to the pathophysiology of Alzheimer's Disease
… risk of developing AD for chronic users of anti-inflammatory drugs, but clinical trials have not shown a consistent benefit of NSAID treatment. In this study, we attempted a more targeted approach to anti-inflammation treatment through chronic, systemic administration of the mIL-1 Trap, …
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A novel particle-based in situ gelling system for delivering hydrogen sulfide at a sustained rate for potential application in glaucoma and retinal neurodegeneration
… therapeutic potential indicated by its roles in anti-inflammation, anti-tumor, ion channel regulation, cardiovascular protection, and anti-oxidation effects. One of the most important therapeutic potential lies in the treatment and management of glaucoma, a condition which is characterized by …
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Mechanisms of Brain Edema Formation in Mouse Models of Intracerebral Hemorrhage
… study was to investigate the mechanisms by which inflammation and thrombin respectively lead to the formation of brain edema following ICH. Our long-term goal is to develop new therapeutic strategies against ICH-induced brain edema by targeting: (1) VAP-1 mediated inflammatory response and (2) …
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Selection and evaluation of ten medicinal plants used, in the Vhembe District, for life-threatening infections
See the attached abstract below
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Identification of Anti-inflammatory and Antioxidant Properties of MangostinXanthones in Adipocyte Reporter Assays
… correlated to inflammatory, adipogenic, and antioxidant status in adipocytes, respectively. Two polyphenolic xanthones, α-mangostin (α-MG) and γ-mangostin (γ-MG) from mangosteen fruit, have been reported to have anti-adipogenic and anti-inflammatory activities. We validated inflammatory and …
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Chemical characterization of proanthocyanidins in purple, blue, and red corn after different milling processes and their anti-inflammatory properties
… effects on several chronic diseases because of anti-inflammatory and antioxidant effects. These effects depend on the degree of polymerization of PA. PA are natural bioactive compounds found in a variety of foods, including barley, cocoa, blueberry, and cinnamon. The objective of this study was …
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Cytotoxic, anti-inflammatory, antibacterial and anti-HIV effects of tabernaemontana elegans leaves and fractions
… properties. There have been no reports about the antimicrobial activity of the plant on selected opportunistic bacteria nor any reported anti-HIV and anti-inflammatory effects of T. elegans leaf fractions as far as literature is concerned. Objective: The aim of the study was to determine the …
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An in vitro and in vivo hepatotoxicity study of an aspalathin- rich green rooibos extract
Hepatotoxicity is an undesirable condition of the liver, often occurring due to the interaction of drugs. Although different methods have been employed in the diagnosis of drug-induced hepatotoxicity, none have accurately proven the hepatotoxic effect of drug-drug interactions or drug-herb …
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Anti-inflammatory and anti-colon cancer potential of yerba mate (Ilex paraguariensis St. Hilaire) bioactive constituents
… The first aim was to investigate the potential anti-inflammatory effect of yerba mate tea (MT) extracts, its constituents and their interactions in LPS-induced RAW 264.7 macrophages. MT extract, decaffeinated MT extract, chlorogenic acid (CHA), caffeine from MT (matein), mate saponins, …
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