Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Anti-infective agents"”.
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DE NOVO DESIGN OF ANTIMICROBIAL PEPTIDES FOR APPLICATION AS ANTI-INFECTIVE AGENTS
Antimicrobial peptides (AMPs) have gathered considerable interest as a new source of antibiotics to tackle the escalating threat of antimicrobial resistance. Adopting a de novo approach enables the rational design of short synthetic AMPs, whilst mitigating concerns of resistance development to …
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Evaluation of bioactivity of QUB1977 from the skin secretion of the frog, Phyllomedusa camba
… It is proven that many of these peptides exhibit antimicrobial, anticancer, antiviral and trypsin inhibitory activities and therefore their potential promising therapeutic value has drawn great attention from numerous researchers<br/>In this study, a novel antimicrobial peptide was isolated and …
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Rapid analysis of pharmacology for infectious diseases.
… of complete pathogen genomes has not led to the anticipated wave of new therapies. One reason for this failure might be that previous efforts at selecting the best targets from the genome have not taken into account information on the properties of associated small molecule ligands.<br/> To …
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Structure, function and inhibition of GcpE, FPPS and GGPPS: targeting isoprenoid biosynthesis for drug discovery
… against these three enzymes are important as anti-cancer and anti-infective agents.
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A retrospective evaluation on the use of Cephalosporins in open-heart surgery
… held in Washington, D.C. on the use and abuse of antimicrobials. Senator Gaylor Nelson of the Sub-committee on the Monopoly of the Select Committee on Small Business stated, "Antibiotics are among the most frequently prescribed drugs in this country exceeded only by the psychoactive drugs." Dr. …
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Invitro antibacterial activity of imidazole and triazole-based antimicrobials against Carbapenem Resistant Enterobacteriaceae
Thesis submitted in fulfilment of the requirements for the degree of Masters of Technology: Biomedical Technology, Durban University of Technology, Durban, South Africa, 2017.
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Optimization of Lead Spectinamide Compounds as Novel Anti-tuberculosis Agents with a Pharmacometric Approach
… Research Hospital designed a novel series of anti-tuberculosis agents, spectinamides – semi-synthetic analogs of spectinomycin. Spectinamides are a potent inhibitor of mycobacterial ribosomes and overcome efflux mediated drug resistance in M. tb. Spectinamides have shown an excellent in vitro …
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A controlled in vitro study of the effectiveness of Withania somnifera herbal tincture and homoeopathic dilution (1X and 6X) against selected gram-positive and gram-negative bacteria
Mini-dissertation submitted in partial compliance with the requirements of the Master's Degree in Technology: Homoeopathy, Durban Institute of Technology, Durban, South Africa, 2003.
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Antimicrobial efficacy of nisin, oregano and ultrasound treatments against foodborne pathogens in ready-to-eat vegetables
Submitted in fulfillment of the academic requirements for the Master of Applied Sciences in Food Science and Technology degree at the Department of Biotechnology and Food Science, Faculty of Applied Sciences Durban University of Technology, Durban, 2020.
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Synthesis and characterization of membrane with molecularly imprinted polymers for selective adsorption of triclosan
Submitted in fulfillment of the requirement for the degree Master of Applied Sciences in Chemistry, Durban University of Technology, Durban, South Africa, 2019.
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Utilization of chlorine dioxide gas in food packaging application
… releasing surface could significantly improve antimicrobial activity of ClO<sub>2</sub> gas in particular packaging system. Once the interior of the package was optimized, it was observed that the amount of ClO<sub>2</sub> gas used per package could be reduced to half of its original dose, and …