Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"Anti-biofilm"”.
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The anti-biofilm activity of essential oils on Listeria monocytogenesand Salmonella Enteritidis
… en varios hábitats. Además de eso, pueden formar biofilms sobre diferentes superficies, lo que hace que su presencia sea muy preocupante. Los biofilms son comunidades microbianas complejas unidas entre sí por una matriz extracelular polimérica. Las células que forman parte de un biofilm son más …
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Electrochemical Detection of Anti-Biofilm Activity Using Unnatural Amino Acid-Containing Antimicrobial Peptides
… because they produce a structure called biofilm, which facilitates antibiotic resistance and is a major cause of chronic infections. In order to combat this threat, new anti-biofilm and antibiotic therapies are being developed and their efficiency must be tested. A series of antimicrobial …
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Recubrimientos anti-biofilm aplicados mediante plasma-polimerización destinados a la industria de manipulación de alimentos y al sector médico
Bacterial biofilms formation in food processing industries and medical applications is a matter of concern due to its ability to adhere and reproduce in different environments, materials and surfaces. Pathogenic microorganisms can easily attach to a surface, develop biofilms, survive at …
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The efficacy of topical agents in the treatment of bacterial biofilms: an in vivo sheep study and an in vitro study.
… has demonstrated the presence of bacterial biofilms on the mucosa of patients with Chronic Rhinosinusitis (CRS), suggesting their role in the pathogenesis of the condition. This thesis contains two separate studies. The studies investigated novel topical therapies by using previously …
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Antibacterial Evaluation of Polygonum Multiflorum
… Recently, it has been shown to contain strong antioxidant, antibacterial and antiviral activity. The extract from the roots of Chinese Knotweed was used to assess its antibacterial properties against a broad spectrum of bacterial species, including 5 Gram-positive (B. cereus, B. megaterium, S. …
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Discovery and Characterization of Small Molecule Inhibitors of Biofilm Formation in Pseudomonas Aeruginosa
Bacterial biofilms are thought to aid in the survivability of a variety of intractable infections in humans. Specifically, biofilm production in Pseudomonas aeruginosa has been shown to play a significant role in chronic infection of cystic fibrosis (CF) patients. Unfortunately, no clinically …
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The Use of Natural Products as Potential Anti-Pseudomonas Agents
… aeruginosa</em> were used as model organisms. Antimicrobial effects were evaluated at various concentrations by using a microtiter plate assay or culture tube assay. The inhibition of biofilm formation was also determined using crystal violet assay. The results indicated that the selected …
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Antibacterial activity and mode of action of the antimicrobial peptide CPF-MW1 against Escherichia coli ATCC 700928
Rapidly emerging antimicrobial resistance and subsequent multi-drug resistance are major global health threats, with the available antimicrobials for treatment being limited. The development of new antimicrobials against Gram-negative bacterial infections is especially challenging due to the …
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Use of electromagnetic stimulation on an Enterococcus faecalis biofilm in root canal treated teeth in vitro
… via instrumentation in conjunction with an antibacterial irrigating solution. The most commonly used irrigant is sodium hypochlorite, often at concentrations toxic to human cells. Electromagnetic wave irradiation is a novel method of disinfection that has been shown to be bactericidal …
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Synthesis and evaluation of novel quorum sensing inhibitors
… as an alternative to, or in combination with antibiotics during the treatment of microbial infections. This chapter is also comprised of a review which details the structure activity relationships of halogenated furanones which have previously been evaluated in the literature. Synthetic routes …
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Novel strategies for the inhibition of biofilm formation on polymer surfaces
… new strategies to prevent bacterial adhesion and biofilm formation on biomaterial surfaces. Two different anti-quorum sensing (QS) molecules, i.e. compounds that inhibit the communication system of bacteria, were employed: 3-butyl-5-(bromomethylene)-2(5H)-furanone and the RNA III inhibiting …
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Controlling Microbial Colonization and Biofilm Formation Using Topographical Cues
… spherical particles as a novel topography-based anti-biofouling coating. It also provides new insights on the effects of surface topography, especially local curvature, on cell–surface and cell–cell interactions during the evolution of biofilms. I investigated the adhesion, colonization, and …
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The Effect of Topography on Surface Behavior of Pseudomonas aeruginosa
Bacterial biofilms are communities of micro-organisms encased a self-produced extracellular matrix. While they form readily in a nature, biofilm formation in man-made systems have economic and health consequences. Prior research demonstrated that topographical features comprised of uniform, …
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Investigating physiological and genetic characteristics of community acquired infections and potential antimicrobial interventions
… potential of having different susceptibility to antimicrobial agents. The purpose of this study was to investigate the effect of antimicrobial agents against community acquired S.aureus and investigate antibiotic characteristics, biofilm formation and gene expression following exposure to an …
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Novel bioactive peptides from the defensive skin secretion of Phyllomedusinae frogs
… predatory attack and microorganism invasion. Antimicrobial peptides (AMPs) act as the first line of self-defence and plays an important role in preventing microbe infections via the skin contact. The skin secretion of phyllomedusinae tree frog contains massive quantities of AMPs, belonging to …
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In vitro evaluation of equine bone-marrow derived mesenchymal stromal cells to combat orthopedic biofilm infections
… and horses. Treatment failure is often due to biofilms that are communities of bacteria that are adhered to a surface or to each other and are surrounded in a self-secreted extracellular matrix. The biofilm matrix protects the indwelling bacteria from being killed by antibiotics and the immune …
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Ancient Triassic Halite as a novel source of antibiotic chemical diversity
… of unexplored natural product chemistry with antimicrobial activity against the clinically relevant ESKAPE pathogens. The capacity of haloarchaea to modulate bacterial quorum sensing via the production of cross-domain induction and inhibitory compounds were also investigated.<br/><br/>Both …
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Small Molecules and Their Conjugates with Peptides: Chemical Strategies to Tackle Resistant Bacteria
Antimicrobial resistance is an increasingly important issue as it renders currently used antibiotics ineffective. There are different approaches how to slow down emergence of resistance, including better stewardship of the current treatments, release of drugs in a more selective way, or discovery …
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Wireless Electrostimulation to Eradicate Bacterial Biofilms
<p>Bacterial biofilms can form on medical implants and cause serious device-associated infections that are incurable by conventional antibiotics because of high-level tolerance to antimicrobials. Common strategies for controlling device-associated infections, such as coating with antimicrobials and …
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MANIFATTURA ADDITIVA FUNZIONALE USANDO RIVESTIMENTI NANOSTRUTTURATI ED ELETTROSPINNING
… sviluppati scaffold funzionali con proprietà anti-biofilm. Va sottolineato che si è deciso di effettuare le prime prove su fibre elettrofilate di polietersulfone (PES) e, successivamente, di estendere l'approccio agli scaffold di polietere etere chetone (PEEK) stampati in 3D. Questa strategia …
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