Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Anti-Microbial Peptides"”.
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Functional Characterization of the Avian Inflammatory Mediators Nod1, MIF and IL-22
… of pro-inflammatory cytokines, chemokines, and anti-microbial peptides. A candidate sequence of chicken Nod1 (ChNod1) was identified with no current evidence of ChNod2. Stimulation of transiently overexpressed ChNod1 and its mutants with mammalian Nod-specific ligands was not conclusive of the …
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QUB-2614: a bioactive peptide from the defensive skin secretion of Odorrana schmackeri
… contain biologically-active compounds, such as anti-microbial peptides (AMPs) and anticancer peptides (ACPs), which are used by biomedical researchers as a source of potential novel drug leads or pharmacological tools.<br/><br/>In this thesis, an AMP was identified in the skin secretion of …
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Paneth Cell-Dependent Intestinal Homeostasis During T. Gondii Infection
… cells in the intestinal crypts which secrete anti-microbial peptides to regulate the microbiota. Breakdown of the symbiotic host-microbe relationship, possibly due to Paneth cell dysfunction, leads to intestinal pathologies such as inflammatory bowel disease (IBD) and infection. The protozoan …
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Modeling host responses to tick feeding and tick-borne flavivirus evolution and dispersal
… and monocytes, wound healing responses, anti-microbial peptides, reactive oxygen species, and C-type lectins. Some down-regulation of transcription during primary infestation was indicated. During secondary infestations, these responses intensified and more cell types infiltrated the bite …
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Herstellung, Expression und Charakterisierung von rekombinanten Antikörpern und Immuntoxinen gegen Phoma lingam, Sclerotinia sclerotiorum und Verticillium dahliae
… resistant plant lines through the expression of antibody fusion proteins, so-called immunotoxins, that were specific for the pathogens and that carried fusion proteins that were toxic to the fungal pathogens. Thus, a prerequisite was the generation of pathogen specific antibodies. Further, these …
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Host-Virus Interactions in Asthma and COPD
… although there is evidence for defective anti-viral interferon (IFN) responses in cells from patients with asthma and COPD. Further investiga-tion of host-virus interactions and their impact on underlying airway dis-ease, may lead to novel therapeutic targets for the prevention of …
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Effect of Advanced Age on the Innate Immune Response to Cutaneous Wound Infection
… and function, reduced expression of cutaneous antimicrobial peptides and aberrant toll-like receptor 2 (TLR2)</p> <p>expression and/or signaling. However, the effect of age on these specific alterations in the innate response has not been well described in a model of cutaneous wound infection. …