Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 71 for “"Anti-Microbial"”.
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Automated synthesis and evaluation of potential new anti-microbial agents
… Mycobacterium fortuitum in a rapid screen for antimycobacterial activity. Many of the compounds from this series were also tested against Mycobacterium tuberculosis, and the usefulness as M.fortuitum as a rapid, initial screen for anti-tubercular activity evaluated. Various deletions were made …
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Synthesis of Nano-Silver Colloids and Their Anti-Microbial Effects
The antimicrobial effects of silver nanoparticles were studied. Silver nanoparticles were synthesized through wet chemistry method, and were dispersed in aqueous suspension. With nanoscale silica particles served as heterogeneous nucleation sites, silver nanoparticles were formed anchoring on the …
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Synthesis and Characterization of Ag and Cu doped DLC Thin Films for Anti-microbial Applications
… to address these issues due to their inherent antimicrobial property and potential to improve adhesion. In this study, Ag and Cu doped DLC thin films were deposited on biomedical grade CoCrMo alloy discs using DC magnetron sputtering. The concentrations of Ag and Cu in the DLC matrix were …
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Synthetic Alkyl Glycolipids as Therapeutic Agents: Their Synthesis as Potential iNKT Cell Stimulators and their Anti- Microbial Properties
… this thesis is the synthesis of glycolipids for anti-microbial studies and to act as iNKT cell stimulatory ligands. Simple glycolipids, L-aspartic acid based glycolipids, glycoglycerolipids and L-serine based glycolipids were explored. Simple galactosyl glycolipids containing O- and N-glycosidic …
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Development of Novel Anti-microbial Plant Essential-Oil Treatments to Reduce the Postharvest Incidence of Botrytis cinerea of Strawberries
… has indicated that they have significant anti-fungal activity. Very little information is available regarding the use of essential-oil compounds for postharvest treatments on California strawberries to reduce the incidence of <em>B. cinerea</em>. The primary objective of this study was to …
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Effect of anti-microbial immunizations in the progression of amyloid and neuroinflammatory pathologies in a mouse model of Alzheimer's disease
… support clinical evidence suggesting that anti-microbial vaccinations protect the brain from neurodegenerative insults. Importantly, this thesis demonstrates the neuroprotective effects of vaccinations against COVID-19.</p>
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Determining the in vitro anti-cancer effects of various novel indoles and an anti-microbial peptide towards a potential treatment of glioma.
… related structures are known to exhibit potent anti-cancer activity against human breast cancer cell lines, and a range of other therapeutic targets. This activity, and other factors such as their biological activity, the fact that they are privileged structures, and the presence of the indole …
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A study comparing the anti-microbial effectiveness of a water-based preparation of hydrastis canadensis to that of an ethanol based preparation on the in vitro growth of candida albicans and escherichia coli
Thesis (Masters in Technology: Homoeopathy), Durban Institute of Technology, Durban, South Africa, 2004
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Structural basis for escaping negative selection by T cell receptor with high affinity for self antigen
… striking contrast to the classical topology of anti-microbial TCRs. Alternatively, escape can occur by weak binding between self-peptides and MHC. We determined the structure of a human autoimmune TCR (MS2-3C8) bound to a self-peptide from myelin basic protein (MBP) and the multiple …
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The role of human breast milk mucus and mucins in HIV-AIDS
Milk molecules such as mucins, antibodies, bactericidal enzymes like lysozymes and fatty acids that lyse bacteria, viral particles and bacterial peptides, offer anti-microbial activity in milk. Despite human breast milk being rich in anti-microbial substances, such as mucin, that protect against …
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Polyandrocarpidines: Antimicrobial and Cytotoxic Compounds From the Marine Tunicate Polyandrocarpa Sp
The marine tunicate Polyandrocarpa sp. contains anti-microbial and cytotoxic metabolites, polyandrocarpidines, whose structures include a polymethylenediamine chain; one nitrogen is acylated with a twelve-carbon fatty acid which contains a cyclopropene ring in conjugation with a diene system, the …
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Functional Characterization of the Avian Inflammatory Mediators Nod1, MIF and IL-22
… of pro-inflammatory cytokines, chemokines, and anti-microbial peptides. A candidate sequence of chicken Nod1 (ChNod1) was identified with no current evidence of ChNod2. Stimulation of transiently overexpressed ChNod1 and its mutants with mammalian Nod-specific ligands was not conclusive of the …
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Inhibitory substances produced by probiotic bacteria for control of food-borne pathogenic and spoilage microorganisms in dips
… ingredients and the presence of prebiotics. The anti-microbial properties of probiotics can also be employed for controlling the spoilage organisms such as yeast and mould. The work described in this thesis focused on the survival of probiotics and their anti-microbial effects in dips. Effective …
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STRUCTURAL AND FUNCTIONAL DETERMINANTS OF CASPASE-11 INFLAMMASOME ASSEMBLY DURING INNATE IMMUNE DEFENSE
… Casp11 inflammasome assembly contributes to anti-microbial host defense but causes sepsis in murine models when dysregulated. To better understand noncanonical inflammasome dynamics within cells, we tracked LPS-inducible assembly of fluorescent-tagged Casp11 in primary macrophages. …
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Pharmacological studies of bioactive compounds from medicinal mushrooms in Northeast of Thailand
… that the local people consume in high quantities annually; some of which are used for medicinal purposes. The local people use them for treatment by boiling with water and drinking the liquor, while some people finely grate the mushrooms, mould them into a bolusand eat it like a tablet as …
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The source, cost and prevention of central venous catheter-related infection
… cost of such infections and the efficacy of an antimicrobial catheter have been undertaken. Thirty patients who required a CVC as part of their medical management and underwent cardiac surgery had the distal tips of their catheters sampled whilst in situ. Sampling took place within 1 h of …
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QUB-2614: a bioactive peptide from the defensive skin secretion of Odorrana schmackeri
… contain biologically-active compounds, such as anti-microbial peptides (AMPs) and anticancer peptides (ACPs), which are used by biomedical researchers as a source of potential novel drug leads or pharmacological tools.<br/><br/>In this thesis, an AMP was identified in the skin secretion of …
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Reversed-Phase HPLC Determination of Alliin in Diverse Varieties of Fresh Garlic and Commercial Garlic Products.
… risk in humans, improving immune system, and anti-microbial, anti-oxidant, and anti-hypertensive activities. The quality of fresh garlic and garlic products is usually related to its alliin content and allicin release potential. This research presents a simple, rapid, and precise HPLC …
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Fabrication of self-assembled zein nanoparticles via microfluidic chip and ultrasonic treatment
… in water or a low concentration of ethanol via anti-solvent precipitation. The traditional method to form the zein nanoparticles is dropping the zein ethanol solution into a bulk water phase with mechanical shearing, which creates the heterogeneous shear environment and uncontrolled for …
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THERAPEUTIC AND SAFETY EVALUATION OF CURCUMIN'S ANTIMICROBIAL AND ANTI-INFLAMMATORY PROPERTIES ON CANINE AND EQUINE
… the therapeutic and safety effect of curcumin’s anti-inflammatory properties. In Exp. 1, two different dosages, 500 mg, SID of 95% curcumin and 250 mg, BID of 95% liposomal-curcumin, were evaluated in ten moderately arthritic dogs over five months. The dogs in the 95% curcumin group had an …
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