Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Anti-HIV Agents"”.
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Development of nitrogen protecting groups and synthesis and complexation of bridged bis-tetraazamacrocycles
… systems may find use as potential anti-HIV agents or for stem-cell mobilization.</p>
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Biochemical Characterization of CXCR4 Interactions With HIV -1, Natural Ligands and De Novo Designed Inhibitors
… Acquired Immune Deficiency Syndrome (AIDS) and HIV-associated dementia (HAD). The entry of human immunodeficiency virus type 1 (HIV-1) into the cell is initiated by the interaction of its surface envelope protein with two cell surface components of the target cell, CD4 and a chemokine …
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Lethal Hypermutation Induced by the Innate Cellular Restriction Factor APOBEC Destroys HIV-1 in Infected Humanized Mice
… case reports of what would become known as AIDS, HIV-1 remains a major health issue both globally and locally. Current antiretroviral interventions are effective at suppressing virus replication; however, they must be maintained for life as the removal of these drugs resulting in the rapid return …
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Mucosal HIV-1 Transmission in Humanized Mice
HIV-1 infects ~6,800 people each and every day, transmitting predominantly through unprotected sexual contact. On a global scale, vaginal transmission now accounts for more than half of newly acquired HIV-1 infections. In developed countries intrarectal infection represents a major form of HIV-1 …
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Desenvolvimento de sistemas de liberação prologando do antirretroviral zidovudina a partir de hidróxido duplo lamelar
… o isolamento de sólidos de alta pureza. O antirretroviral zidovudina (AZT) apresenta, como principal limitação, o baixo tempo de meia vida plasmática, sendo necessária a administração de várias doses diárias, e assim favorecendo o surgimento de reações adversas. Nesse contexto, o presente …