Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"Anti-Depressant"”.
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Serotonin receptor mechanisms in anti-depressant action
… major depression to treatment with serotonergic antidepressants. To assess the effect of repeated treatment with selective serotonin re-uptake inhibitors (SSRI's) on the function of central 5-HT2c receptors I used the 5-HT2C receptor agonist, m-chlorophenylpiperazine (m-CPP) as a 5-HT2c probe in …
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Serotonin mediated effects on food intake, feeding body weight and subjective variables
… the effects of the 5-HT reuptake inhibitor and anti-depressant fluoxetine on food intake and choice, body weight and subjective states in both non-depressed normal-weight and obese subjects. The third and final impetus arose from the observation that, in rats, the expression of meal-induced …
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Quality of Depression Treatment in Type 2 Diabetes: Exploring the Effects of Race and Ethnicity
… treatment (OR=2.09 95% CI[1.20, 3.64]) and anti-depressant use for ≥60 days (OR=2.14 95% CI[1.15, 4.02]). Ethnicity, education and insurance status moderated the effects of HT. Yet guideline-concordant depression care is low among depressed Black Americans, including those with comorbid …
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A meta-analysis of Prozac and three psychotherapies in the treatment of unipolar major depression
… due to its reputation as a new, very effective anti-depressant. This study used a meta-analysis to compare three psychotherapies with medication: 1) cognitive therapy, 2) behavioral therapy, 3) cognitive-behavioral therapy, and 4) the prescription of Prozac. New methods of meta-analysis …
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A Comparison Study of Depression and Wellness Among Undergraduate College Students Seeking Degrees in the Helping Professions
… depression, and 36% of college students taking anti-depressant medication (Huff, 2011). Therefore this quantitative study is important to investigate depression not only as it relates to undergraduate college students but more specifically, to undergraduate college students interested in …
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Analysis of the behavioural effects of barley and sertraline in two in-vivo models of stress.Anti-depressant and anti-nociceptive effects of barley in mice and sertraline effects on anxiety in the offspring of prenatally-stressed rats
To prove the post-natal depression model, the antidepressant sertraline, was assessed in rat mothers (n=14) divided into Prenatally Stressed (PS) and Non-Stressed (NS) groups. The data failed to support the hypothesis that ‘the progeny of 10mg of sertraline-treated PS mothers displayed less anxiety …
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Expression and regulation of the rate-limiting enzymes of the kynurenine pathway in the mouse brain
During the mid-1900’s, early anti-depressants were developed to increase levels of catecholamines within the brain, leading to the theory that depression symptomology was a result of an imbalance of neurotransmitters within the brain. To date, the catecholamine theory of depression is still held to …
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The Impact of Efficacious Treatments for Major Depressive Disorder on Remission Rates of Specific Symptoms: A Re-Analysis of the Treatment of Depression Collaborative Research Program
… (CBT), Interpersonal Psychotherapy (IPT), and anti-depressant medications - are equal in their efficacy, and superior to placebo. However, it is unclear whether rates of remission for certain types of symptoms differ among treatments with theoretically different mechanisms. This study …
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The development of Deoxyribonucleic Acid (DNA) based methods for the identification and authentication of medicinal plant material.
… with clinical evidence to support its use as an anti-depressant. A fundamental requirement of the new legislation is to prove the identity of the plant material in question. This is currently achieved via morphological and chemical methods, neither of which are ideal. A wide range of DNA based …
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Immune and stress factors in the pathophysiology of the mdx mouse model of Duchenne Muscular Dystrophy
… DMD and examined the effects of the tri-cyclic antidepressant, amitriptyline on behaviours. Amitriptyline had anti-depressant and anxiolytic effects in the mdx mice possibly through effects on stress factors such as corticotrophin-releasing factor (CRF). This antidepressant also reduced skeletal …
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The role of subjective well-being in mediating the psychological impact of obesity
… approach was taken that included both quantitative cross-sectional survey data based on validated constructs that combine to measure SWB and qualitative longitudinal data based on unstructured interviews. The ideographic approach brought a narrative to the nomothetic data and elevated the …
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Investigating the Enteroendocrine - Brain Axis: Ghrelin Cell and ECL Cell Physiology and Ghrelin Action on Mood and Complex Eating
… depressive-like behavior. Ghrelin has antidepressant effects, which become obvious following chronic stress. In the first part of my thesis, I found that this effect was mediated by neurogenesis. I observed that chronic stress reduces neurogenesis more severely in the ventral dentate …
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In an era of neoliberalism and inequality can self-transcendence foster conscientisation for social change?
… percentage rate of consumption in prescriptive anti-depressant drugs, I would argue that it is perhaps the pressures from living in a world, as described above, that people are opting out of life and choosing death by suicide. Examining, recent structural changes in our Irish adult and community …
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An analysis of treatment retention and attrition in an Australian therapeutic community for substance abuse treatment
… entry. Clients receiving medication (primarily anti-depressant medication) were more likely retained at 14 weeks. Older clients (24 – 29 years, and 30 – 50 years) were significantly more likely to drop out of treatment by the 14 week stage compared with the younger client group (17 – 24 years). …
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Student Psychotropic Drug Use, Past Therapy Experience and Length of Therapy
… hypothesized that students who reported taking anti-anxiety or anti-depressant medications would stay in therapy longer than students taking other types of psychotropic medications will. Participants (n = 279) were collected from a pre-existing database and included students who received …
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Optimisation of protein and lipid extraction from low-value fish sources and investigation of high-value applications
… poutassou), boarfish (Capros aper), and Atlantic herring (Clupea harengus), and to assess the effects of such products on the recipient’s gut microbiota. In Chapters 3 and 4 the proximate (biomass in terms of gross components, e.g. water, ash, protein and lipids) and gut microbial …
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Low Social Support as a Risk Factor for a Major Depressive Episode in Canadian Community Dwelling Seniors
… Therapeutic Classification (ATC) Drug codes for anti-depressant usage. Demographic characteristics and health characteristics of respondents and non-respondents were examined and compared. The 12-month prevalence and 2- and 8-year incidence proportions of MDE were estimated. Multivariate logistic …
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Immunological and behavioral consequences of high-fat diet feeding in mice
… modulation of motivation to obtain reward and anti-depressant activity, and IL-1RA has been implicated in the mediation of central leptin resistance. To examine if these cytokines contributed to the increased saccharin consumption and other behaviors observed in fasted HFD mice, we measured …
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Where Does it Stem From? - Functional Neuroimaging of Monoaminergic Brainstem Nuclei in Altered States of Consciousness: Translational, Diagnostic and Therapeutic Implications
… raphe functionality might underpin psychedelic anti-depressant effects. Altogether, these studies demonstrate that monoaminergic nuclei dysfunction might be a hallmark common to various different ASCs – and that functionality of these brainstem sources of non-classical transmitters might …
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Functional Studies of Novel Bioactives From Complex Host-Microbiomes as Drug Leads for Cancer, Infectious Disease, Depression and Pain
… can lead to false indications of cytotoxicity or antifungal activity. The elucidation of a new theopapuamide analog by CID-MS from Theonella invaginata indicates the high level of peptide diversity found within this Family. Two functional studies of marine natural products contribute to the …