Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Annexin A2"”.
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Mechanisms of Cell Surface Trafficking and Potential Functions of Extracellular Annexin A2
Annexin A2 (AnxA2) belongs to a family of Ca2+-dependent phospholipid binding proteins. AnxA2 is abundantly expressed in the cytosol of many different cell types and is translocated to the outer surface of the plasma membrane in response to elevated concentrations of intracellular Ca2+. It is known …
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The mechanism of action of the scorpion toxin, chlorotoxin, a bioinformatics approach
… with invasion and metastasis of GBM cells. Annexin A2 is involved in angiogenesis, and it is overexpressed in GBM. MMP2 and annexin A2 are potential targets for effective glioma therapy. Chlorotoxin is a promising toxin peptide for glioma targeted therapy. Chlorotoxin decreased migration and …
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Investigating the protein targets of the neuroprotective E3 ligase, CHIP
… of synucleinopathy with mild proteotoxic stress. Annexin and other calcium-binding proteins, in particular Annexin A2 and its interacting protein S100-A11, were the most over-represented proteins in the CHIP KO cortical neurons. From this comprehensive target discovery investigation, I have …
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Signal transduction by the 5-HT2A receptor and its H452Y polymorphic variant
… possible interactions of the 5-HT2AR with the Ca2+-binding proteins annexin A2, S100B and the annexin A2 partner p11, together with the functional consequences of these interactions. Co-immunoprecipiation and GST-fusion protein studies show that annexin A2 binds specifically to the 5-HT2AR ct. …
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Proteomic Analysis of Human Mesenchymal Stem Cell Aging during serial sub-culture
… ii Poly (rc)-binding protein, Alpha-tropomyosin, Annexin A2, and Galectin 3 were down regulated. Similarly, it was found that Vimentin, Beta actin, Nucleophosmin, and Heat shock protein 70 (Nterminal frag) showed up regulation in protein expression at initial passages and down regulation at late …