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Showing 1 to 17 of 17 for “"Anion transport"”.
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Cation and Anion Transport in a Dicationic Imidazolium-Based Plastic Crystal Ion Conductor
… (PFG) NMR. We quantify distinct cation and anion diffusion coefficients as well as the diffusion activation energies (Ea) in this dicationic imidazolium-based OIPC. Our studies suggest a change in transport mechanism for the cation upon varying thermal and magnetic treatment (9.4 T), …
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Neutral receptors for anion recognition: synthesis, selectivity studies and transport properties
… urea groups that can function as selective anion receptors and efficient anion transmembrane transporters. Two new asymmetric ureidic receptors L1 (1-(1H-indol-7-yl)-3- (quinolin-2-yl)urea) and L2 (1-(quinolin-2-yl)-3-(quinolin-8-yl)urea), shown in Figure 1, have been synthesised and their …
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Functional and Molecular Aspects of Xenobiotic Transport in Choroid Plexus
… brain. The CP not only secretes CSF, but also transports potentially toxic xenobiotics and waste products of neural metabolism to the blood for eventual clearance in kidney and liver. For several decades it has been known that the CP is actively involved in removing organic anions and other …
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The design of synthetic transmembrane carriers for anions
… receptors found to facilitate the transmembrane transport of anions in synthetic vesicle systems. A series of structurally simple thioureas were found to function as efficient Cl-/NO3- and Cl-/HCO3- antiporters while the corresponding ureas were inactive. Of these receptors, a simple …
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Aminocyclodextrin Ion Channels: Development of a Model for Ligand Gating and Investigations of the Effects of Channel Structure on *Transport Properties and Ion Selectivity
… ion channel was highly active and selectively transported anions, the requirements for the number of aminopentabutylene glycol substitutions were not known. beta-Cyclodextrin channels with four and two aminopentabutylene glycol chains and beta-cyclodextrins substituted with a …
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Synthesis and Study of Biomimetic Ion Channels: (1) Toward the Development of a Cyclic Peptide-Based Redox-Gated Channel, and (2) Investigations Into the Effect of Pore Size on the Ion Selectivity of an Aminocyclodextrin Channel
… macrocycle was synthesized and its transport properties were compared with those of an analogous channel with a larger beta-cyclodextrin pore. The anion transport profile of the alpha-cyclodextrin channel (ClO 4- > I- > Br- > NO3- > Cl-) differed from that of its beta-cyclodextrin …
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Towards Responsive Squaramides: Anion Recognition, Sensing, and Transport
Anions play a crucial role in both biological and environmental contexts to such an extent where the absence or the overabundance of anions can lead to severe health implications and environmental concerns. The recognition of the universal significance of anions has led to an explosion of research …
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The Structure-Function Relationship of Prestin: from an Evolutionary Perspective
… outer hair cells. It belongs to a distinct anion transporter family called solute carrier protein 26A, or SLC26A. Members of this family serve two fundamentally distinct functions. While most members transport different anion substrates across a variety of epithelia, prestin (SLC26A5) …
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An Anion Selective Aminocyclodextrin Ion Channel: Ion Selectivity, pH Sensitivity and Potential as a Scaffold for Light Gating
… functionalized pentabutylene glycol chains. Ion transport through the channel gauged using 23Na NMR and fluorescence spectroscopy indicated high ion transport activity, comparable to natural ion channels. The fluorescence studies also indicated that the ion channel was highly anion selective with …
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Transport von Paraaminohippursäure, Furosemid, Hydrochlorothiazid, Cimetidin, 11-Deoxycorticosteron und Taurocholat an der basolateralen Membran proximaler Nierentubuli
The renal basolateral transport system is an efficient system for secretion of a wide range of different drugs. One important part of this system is the organic anion transport system (OATS1), which is known for its wide range of substrate-specifity. Previous studies could demonstrate the …
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Characterization of a human renal organic anion transporter
The renal excretion of organic anions, including a variety of endogenous substances, xenobiotics and their metabolites, involves an organic anion transport system with multiple specificity. The well characterized basolateral uptake step of this process involves the organic anion transporter 1 …
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Capturing irradiation-enhanced corrosion of zircaloy-4 with a charge-based diffusion/drift phase field model
… for both diffusion-and drift-based oxygen anion transport in Zircaloy-4 by including the effects of radiation-induced evolution of SPPs in changing the contribution of a local charge transport inequality through their depletion and release of iron. By addressing the imbalance in charged …
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Electrochemical synthesis and characterisation of polypyrrole/chitosan films doped with molecular anions
… and release of methyl orange (a model anionic dopant), dexamethasone (an anti-inflammatory drug) and oxacillin (an antibiotic). All drug-doped films were grown at a constant potential of 0.80 V vs SCE until a charge density of 0.25 C cm-2 was achieved. Initially, a novel approach was …
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Squaramide- and Urea-based Supramolecular Gels: Characterization and Environmental Applications
… evaluate the effect of an indolyl substituent on anion binding and transmembrane anion transport properties. Appendix B presents a small library of acyclic squaramides (B1–B5) investigated as ionophores for the potentiometric detection of non-steroidal anti-inflammatory drugs (NSAIDs).
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Design and synthesis of bioactive small molecule anionophores inspired on natural products
… proteínas de membrana, esto es facilitar el transporte de aniones a través de membranas lipídicas, lo cual es un objetivo de gran relevancia por las potenciales aplicaciones que presentan estos compuestos en el tratamiento de enfermedades derivadas del funcionamiento anómalo de estas …
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Cloning and characterization of organic anion systems in the adrenal cortex and their role in steroid release
… and medicine. Previous studies have suggested transporter(s) may participate in this process. In this study the characteristic features of the previously demonstrated ROAT1-like exchange transport system in bovine adrenal cells were investigated with representative substrates. Corticotrophin …