Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 48 for “"Animal study"”.
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Comparison of progression of diffuse axonal injury with histology and diffusion tensor imaging
… fiber tracts. To date, only one correlative animal study has been carried out to investigate the DTI relationship to TAI, and it has reported a relationship between DTI changes and TAI. No other animal study has validated the correlation between DTI and TAI. Therefore, this study is the …
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Human intestinal microbiota and metabolites they produce in relation to host health
… used in both the manufacture of yoghurt and an animal study. In total, 38 B. longum strains, obtained from infants and adults, were assessed in vitro for the selected probiotic traits using a combined phenotypic and molecular approach. Differentiation of the 38 strains using amplified ribosomal …
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Development of Virus-like particles (VLPs) Based Vaccines Against Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) and Porcine Epidemic Diarrhea Virus (PEDV)
… of the polymeric nature of VLP. The first animal study evaluated the efficacy of 4 VLP based vaccine candidates against PRRSV in mice. These 4 vaccines incorporated 2 B-cell epitopes (61QAAIEVYEPGRS72 and 89ELGFVVPPGLSS100) and 2 T-cell epitopes (117LAALICFVIRLAKNC131 and …
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Risk-Sensitive Foraging in Humans Budgeting Time: Correlated with Real-World Financial Situation
… theory has been studied extensively in non-human animals. Using models developed through animal-study, researchers have recently begun to examine how humans make decisions with regard to resource-expenditure. Using a computer-based task, the proposed study investigated risk-sensitive …
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Risk-Sensitive Foraging in Humans Budgeting Time: Correlated with Real-World Financial Situation
… theory has been studied extensively in non-human animals. Using models developed through animal-study, researchers have recently begun to examine how humans make decisions with regard to resource-expenditure. Using a computer-based task, the proposed study investigated risk-sensitive …
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The nature of leukocytic response to mouse mammary tumor implants in C3H/HeJ mice with and without anticoagulation
… is a common form of cancer used for experimental animal study. This investigation was designed to study the nature of leukocytic response to mouse mammary tumor implants in C3H/HeJ mice with and without anticoagulants. The main thrust of the research was in three areas: first, to develop a …
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Adhäsions- und Nidationsprophylaxe nach i.p.-Implantation von SCOV3.ip-Zellen in SCID-Mäuse mittels Icodextrin, Hyaluronsäure und physiologischer NaCl-Lösung im Vergleich
… tumour cells is possible. The aim of the present animal study was to evaluate the efficacy of the three barrier products icodextrin (Adept®), hyaluronic acid (Hyalobarrier®-Gel) and physiologic saline on adhesion formation as well as on tumour recurrence after surgery of ovarian carcinoma. Forty …
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Development of an Artificial Meniscus Implant
… as a meniscus replacement. To validate this, an animal study was designed to access durability as well as the biocompatibility and chondroprotection of the implant. A sheep shaped implant was designed for this test and cadaveric work was performed to provide a final design with proper fit and …
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Development of a Non-Contact Fluorescence Tomography System with Appropriate Reconstruction Techniques
… imaging devices. It is mainly concerned with studying the effects of prototype drugs in small animals, following day by day the evolution of the disease in vivo. Amongst the imaging techniques available, fluorescence based imaging is very popular due to the simplicity of the experimental …
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Application of a High‑Resolution Computed Radiography System in Detecting an Iodinated X‑ray Contrast Agent: Small Animal Phantom Study
… contrast agent, in a phantom mimicking small animal tumor model.</p> <p>The first phase of the project was dedicated to a comprehensive assessment of CR image quality by measuring presampled Modulation Transfer Function (MTF), Noise Power Spectrum (NPS), Relative Standard Deviation of Noise …
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rhBMP-2 zur Knochenaugmentation bei transgingivaler Implantateinheilung
The aim of this study was to investigate the influence of rh-BMP-2 on the reconstruction of bone defects at the buccal side using dental implants in a animal study. The results of this study contribute the advancement of a transgingival immediate implantation. We inserted 24 dental implants (with …
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Effect of Soy Protein, Isoflavones and Methionine Supplementation on Lipid Metabolism
… where the effect was more pronounced. A second study was conducted to evaluate dietary isoflavones and methionine concentrations on gerbils. Results from these studies indicated that total cholesterol levels were significantly lower (p < 0.05) in the soy-fed group, compared to casein-fed group, …
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Small molecule kaempferol, a novel regulator of glucose homeostasis in diabetes
… insulin-deficient diabetic mice. For the first animal study, kaempferol was supplemented in the diet to determine whether it can prevent insulin resistance and hyperglycemia in high fat (HF) diet-induced obese mice or STZ-induced obese diabetic mice. For the second animal study, kaempferol was …
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Neuroprotective Effect of Human Mesenchymal Stem Cell on Dopaminergic Neurons by Anti-inflammatory Action
… role in the pathogenesis of PD. The present study was to evaluate effect of human bone marrow-derived mesenchymal stem cell (hMSCs) on modulation of neuroinflammation. We used lipopolysaccharide (LPS)-induced in vitro and in vivo inflammation models to investigate whether hMSCs have a …
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Prostacyclin-Inhalation in Kombination mit Almitrine zur Therapie des akuten Lungenversagens
The aim of this prospective controlled animal study was to investigate a possible additive effect of combined inhaled prostacycline and intravenous almitrine bismesylate (ALM) on pulmonary ventilation-perfusion ratio in acute lung injury (ALI) compared to inhaled prostacycline or intravenous ALM …
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Tissue engineering of co-cultured skin substitutes using biocomposite membranes based on collagen and polycaprolactone
… assay. The following in vivo animal study on athymic mice revealed early complete wound healing in 10 days and good integration of co-cultured skin substitutes with adjacent mice skin structures. Thus the co-cultured skin substitutes based on 1:20 collagen: PCL biocomposite …
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Etablierung eines Modells zur Testung neurokognitiver Störungen nach kardiopulmonaler Reanimation bei Schweinen
… in this randomized controlled laboratory animal study. Animals were anesthetized and mechanically ventilated before arterial and pulmonary artery catheters were inserted. CA was induced electrically and after randomization of the animals in 2 groups (n=7/group) left untreated for either 5 …
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Effekte wiederholter Erstellung der pulmonalen Druck-Volumen-Kurve auf Gasaustausch und Hämodynamik beim experimentellen Lungenversagen
The present experimental animal study on eight female pigs investigated the effects of the repeated construction of the Pressure-Volume Curve in acutely injured lungs, exemplary here in an experimentally induced ARDS. For this investigation we used a built-in tool in a commercially available …
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The Role of Arginine Vasopressin Receptor 2 in Microvascular Hyperpermeability During Severe Sepsis and Septic Shock
… leakage. Thus, the overall goal of the current study was to investigate the most important mechanisms of vascular leakage during severe sepsis and propose a novel therapeutic strategy for this condition. Arginine vasopressin (AVP), a hypothalamic hormone, has been used exogenously in sepsis to …
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Needle-free interstitial fluid acquisition using a Lorentz-force actuated jet injector
… novel ISF acquisition method. A micro-CT imaging study identifies the magnitudes of injected jet speed that will influence injectate delivery to specific skin layers. A histology study highlights the differences in tissue damage between needle injections and jet injections. A new tool for …
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