Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 365 for “"Animal Studies"”.
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Nonalcoholic steatohepatitis (NASH) : animal studies of interactive hepatoxicity
… options are currently available. However, animal models of NASH now provide unique opportunities for study of this disease in the laboratory setting. This thesis employs a dietary animal model, which restricts methionine and choline intake, to replicate aspects of the injurious process in …
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Sex as a Biological Variable in Preclinical Animal Studies with an Infectious Disease Exemplar.
… framework, which was developed in a first-line animal model using C57BL/6 mice to evaluate the safety of a novel therapy against C. difficile, High temperature requirement-A (HtrA). This body of work investigates the contribution of sex-associated biological factors to preclinical safety …
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A Dis-Ability Perspective on the Stigmatization of Dissent: Critical Pedagogy, Critical Criminology, and Critical Animal Studies
… education, criminology, and peace and conflict studies. Within those three disciplines, this project interweaves newly emerging fields of study together, including critical animal studies, eco-ability, disability studies, environmental justice, transformative justice, green criminology, …
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Trajectory features as surrogate measures of the nanoparticle-microenvironment interaction space
… technologies has slowed; in 1995, the ratio of animal studies to FDA-approved drugs was 19:1 and the ratio of animal studies to clinical studies was 7:1. Fifteen years later in 2010, the ratio of animal studies to FDA-approved drugs was 4000:1, and the ratio of animal studies to clinical studies …
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Using Animals: the use of non-human animals from the material to the metaphorical, 1100-1380
This thesis applies Animal Studies theory to a selection of texts from medieval literature and visual culture. In particular, it is concerned with the ways that the ‘fact of interaction’ impacts on an evaluation of non–human animal (NHA) and human–animal relationships. The thesis re–examines a …
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A critical benefit analysis of artificial gravity as a microgravity countermeasure
… physiological systems, though few ground-based studies have been performed in comparison to other countermeasures. The current analysis attempts to elucidate the effectiveness of artificial gravity by directly comparing results of previously published and unpublished deconditioning studies with …
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Studies of the cardiovascular effects of inotropic agents and vasodilators on the pulmonary and systemic circulation in man
… adverse as well as beneficial effects. Although animal studies can give some indication of the mode of action, such drugs should be evaluated both by measurement of their effects on the circulation and by appropriate clinical trials to determine if there is any useful benefit. In this …
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OPTICAL COHERENCE TOMOGRAPHY FOR NEUROSURGEY AND CANCER RESEARCH
… paradigm of surgical guidance and preclinical animal studies. The design and development of OCT devices for neurosurgery guidance and novel imaging algorithms for monitoring anti-cancer therapy have been pursued in this work. A forward-imaging needle-type OCT probe was developed which can fit …
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Ethical entanglements: human-animal relationships in modern and contemporary Spain
… questions. First, how do analyses of human-animal relationships throughout the twentieth and twenty-first century Spanish literature suggest more inclusive visions of multispecies community? Second, what can these representations of animal protagonists tell us about the ways in which authors …
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Bestiaries the animal and the human in Mila Kundera's The Unbearable Lightness of Being and J.M. Coetzee's Disgrace
… that the border between the human and the animal passes "first of all as a mobile border within living man". At stake in the construction of this border is a division of the human and the animal into separate and homogenous groups, and subsequently a denial of a multiplicity of life forms …
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Between Species: Biopolitics, Resistance, and Interspeciesality
… My Year of Meats—in the context of posthumanist animal studies. A Foucauldian biopolitical lens foregrounds the inextricably linked ways that both human and nonhuman animal bodies are governed and controlled in a biopolitical era. Each chapter focuses on textual links between speciesism and the …
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Development of a chronically implanted microelectrode array for intraneural electrical stimulation for prosthetic sensory feedback
… designs were developed and implanted in rabbit animal models and monitored for chronic functionality evaluated using both neurophysiological and behavioral tests. Animal studies have demonstrated single channel implant functionality of up to 129 days. The relative merit of the designs is …
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“The Flow of Blood in Nature” Franz Marc’s Animal Theory
This thesis argues for a coherent theory of the animal in the written and visual works of the German Expressionist painter, Franz Marc. By contextualizing Marc’s animal theory within the history of animal studies, this thesis will analyze how Marc’s animal theory corresponds with several central …
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Feedback Control of Phased Array Electromagnetic Hyperthermia Using MRI Temperature Mapping
… hyperthermia system intended for small animal studies was designed and built. (2) A new technique is presented that allows noninvasive mapping of the relative phase patterns of the microwave fields inside a phantom. (3) An MRI-based technique is presented for closed loop spatial steering …
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Development of a Fourier Domain Low Coherence Interferometry Optical System for Applications in Early Cancer Detection
… through scattering standard experiments and animal tissue imaging. Next, the new processing method is validated by a series of absorption phantom experiments. Additionally, the nuclear sizing capabilities of the fLCI technique are validated by a study measuring the nuclear morphology of in …
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A Unifying Account of Technological Knowledge: Animal Construction, Tool Use, and Technology
… refer to a few cases, usually from chimpanzee studies, as special and unusual in the animal kingdom and whose similarities to human tool use can be explained through some shared evolutionary heritage. However, new observational and laboratory animal studies demonstrate that tool use and the use …
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Behavioral Models of Cocaine Use Disorder
… with substance use disorder has made creating animal models with high predictive validity difficult. One tactic to help translate results from animal studies to humans is to separate the symptoms of substance use disorder into two broad categories of dysregulated drug taking and dysregulated …
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The effects of early developmental stress and exercise intervention on neurodegeneration in a rat model of Parkinson's disease
… hypothalamic-pituitary-adrenal axis activity. Animal studies have shown that maternally separated rats exhibit increased anxiety- and depression-like behaviour in adulthood, although other evidence shows hyperactivity and impulsivity in such cases. Given that stress has these behavioural …
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Conformal Additive Manufacturing for Organ Interface
… channels and the organ cortex. Large animal studies reveal microfluidic biopsy samples contain rich diagnostic information, including clinically relevant biomarkers of ischemic pathophysiology. Overall, these results suggest microfluidic biopsy via 3D printed organ-conforming …
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