Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 97 for “"Animal Experimentation and Research"”.
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The influence of anesthesia and nicotine on dopamine signaling in the rat dorsal striatum
… is highly innervated by dopamine neurons and is involved in movement control (dorsal striatum) reward learning (ventral striatum). Fast-scan cyclic voltammetry (FSCV) is a technique that uses microelectrodes (diameter ~5 μm, length ~150 μm) to monitor dopamine signaling in the brain. …
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The Pacemaker Function of the Small Intestine
… found to be 18 to 19 per minute in the duodenum and 14 to 15 per minute in the ileum. In the terminal ileum there was somewhat of a reversal in the gradient of rhythmicity.</p> <p>Additional evidence is presented to suggest that a duodenal pacemaker controls the normal frequency of contractions …
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Concurrent Infections of TRYPANOSOMA EQUIPERDUM and TRICHINELLA SPIRALIS in Mice
… infections of <em>Trichinella spiralis</em> and <em>Trypanosoma equiperdum</em>, the survival times vary in the early stages of the <em>Trichinella</em> infection. On Days 1 and 4, the mean survival times are significantly increased, and on Days 3 and 7 they are markedly decreased. This …
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Impact of Oxytocin and Tetrahydrocannabinol on signs of fear in the rat
… post-traumatic stress disorder (PTSD). Previous research suggests that pre-treatment of intranasal OXT attenuates signs of fear in rats; however, the impact of intraperitoneal (i.p) OXT pre-treatment on signs of fear in rats is unknown. We also explored the effects of delta-9 (psychoactive …
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Seasonal infection of invasive Brook Stickleback (Culea inconstans) by the nematode Contracaecum multipapillatum at Turnbull National Wildlife Refuge, Washington
… was first identified in Washington state in 1999 and has since established high population densities at Turnbull National Wildlife Refuge (TNWR). Fish parasitized by Contracaecum multipapillatum, a nematode known to infect zooplankton, piscivorous birds, and mammals, have previously been found at …
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Identifying notch-regulated genes using a specific notch signaling inhibitor
… a balance between bone resorption by osteoclasts and bone formation by osteoblasts to maintain skeletal integrity. Disruptions to this equilibrium can lead to pathological conditions such as osteoporosis. Osteoclasts originate from macrophages, and their differentiation is regulated by several …
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Concurrent Infection of TRYPANOSOMA MUSCULI Kendell, 1906, and SCHISTOSOMA MANSONI Sambon, 1907 in Mice
… infection of <em>Trypanosoma musculi</em> and <em>Schistosoma mansoni</em> in mice, and (2) by obtaining <em>Trypanosoma lewisi</em> immune rat serum (ablastin) and injecting it into <em>S. mansoni</em> infected mice. These procedures were followed on days 4, 14 and 28 of <em>S. …
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Walleye (Sander vitreus) do not exhibit an aggregative predatory response to larval White Sturgeon (Acipenser transmontanus) in the Upper Columbia River in Lake Roosevelt, Washington
… project aimed to determine whether Walleye (Sander vitreus) exhibit an aggregative predation response to larval White Sturgeon (Acipenser transmontanus) drifts in the Lake Roosevelt system which is a reservoir of the Columbia River in Washington State. Populations of sturgeon are threatened …
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Effect of Sensory Additives on Sow Lactation Performance, Subsequent Reproductive Performance, and Nursey Pig Performance
… a sensory additive on sow lactation performance and nursery pig performance. Five groups of sows were farrowed, three during winter (October, December and January) and two during summer months (June, July, August). Sows were weighed, and back fat depth was measured, at 110 d of gestation prior to …
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Evaluation of the Effect of a Lippia organoides Essential Oil Extract on Clostridium perfringens Proliferation In Vitro and Necrotic Enteritis in Broiler Chickens
<p>The purpose of the present research was to assess the effects of essential oils derived from the plant Lippia organoides on performance parameters, intestinal integrity, and necrotic enteritis (NE) in broiler chickens. To do this, a previously established challenge model for NE was utilized …
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The Role of the Parotid Salivary Glands in the Regulation of Insulin Secretion
<p>Stress of handling, partial or complete sialoadenectomy, and the administration of parotid hormone (PH), sodium fluoride (NaF), or guanidino-succinic acid (GSA) were examined for effects on fasting plasma glucose and insulin or effects on intravenous glucose tolerance in male Sprague-Dawley …
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Pathogenesis of Dry Eye in Graft Versus Host Disease (GVHD): Role of Ocular Mucins and Conjunctival Fibrosis
… offers a possible cure for hematologic cancers and other hematologic disorders. Unfortunately, despite the increasing survival rate of patients, the quality of their life is adversely affected by the allogeneic bone marrow transplantation’s major side effect i.e Graft vs. Host Disease (GVHD). …
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Effects of Food Consumption on Cell Proliferation in the Brain of Python regius
<p>Neurogenesis is an important and vastly under-explored area in reptiles. While the ability to generate new brain cells in the adult mammalian brain is limited, reptiles are able to regenerate large populations of neuronal cells. Pythons exhibit a characteristic specific dynamic action (SDA) …
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Downregulation of miR-10a-5p as a Potential Therapeutic Target to Improve the Detrimental Effects of Post-stroke Social Isolation
… isolation is detrimental to health. Isolation and loneliness are linked to all-cause mortality and accelerated disease progression in patients with cancer, dementia, and vascular disease. The number of individuals that live alone is increasing in our society, especially in the elderly, and …
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Age-changes of the Neuronal Component of Meissner Corpuscles in the Mouse Digital Pad
… Direct microscopic observation, photomicrographs and camera lucida tracing were utilized. From qualitative observation, the corpuscular neurites were found to undergo morphological age-related changes of diameter, tortuosity, varicosity, branching and terminal expansion size. Quantitative …
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The Effect of Hypercholesterolemia on the Membrane Lipids, 3-0-[¹⁴C] Methylglucose Transport, and 2,3-Diphosphoglycerate Levels in Rat Erythrocytes
<p>An increase in dietary cholesterol and cholic acid will produce hypercholesterolemia in rats. For ten months, two groups of rats (six in each group) were fed commercial rat pellets (control group) or rat pellets plus cholesterol (1%) and cholic acid (0.25%) (experimental group). A blood sample …
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The Effect of ESCHERICHIA COLI Endotoxin on the Cat Periapical Tissues
… to three concentrations of endotoxin solutions and to a sterile saline control solution was examined in six adult cats. The maxillary and mandibular cuspids were isolated and the pulps extirpated with barbed broaches. The four solutions (1, 10, 100 μg/ml endotoxin, and saline) were then injected …
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A tractable nematode model for the emerging fungal pathogen, Candida auris
<p><em>Candida auris</em> is an emerging multidrug-resistant opportunistic fungal pathogen. It</p> <p>poses a significant threat to immunocompromised patients and those with prolonged stays in</p> <p>healthcare facilities. <em>C. auris</em> spreads rapidly in health care facilities through …
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The role of Wt1 in Müllerian duct development
… utilizes the Cre-lox system to delete exons 8 and 9 of <em>Wt1</em>, disrupting the DNA binding capability of the protein. Simultaneously, a nuclear red fluorescent protein is activated in cells expressing the recombined allele. After validating and characterizing this allele, we drove <em>Wt1 …
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Distribution and Proportion of Immunoreactive Neuron Specific Enoclase Containing Cells in the Rat Pineal Gland
<p>The distribution and proportion of cytoplasm containing immunoreactive neuron specific enolase (NSE) in the rat pineal have been investigated. Step serial sections of the pineal glands of 7 male Sprague-Dawley rats were stained for NSE using an indirect immunoperoxidase method. The volumes of …
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