Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 64 for “"Anhedonia"”.
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Resource allocation in dysthymia and anhedonia
Prior psychophysiological research has shown that dysthymic individuals are hyporesponsive during information processing tasks. This can be interpreted as evidence of a deficit in the availability or allocation of processing resources. The present research addressed this possibility by comparing …
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Cocaine Use Disorder: Anhedonia and Emotional Flattening
Anhedonia, the reduced capacity to experience or pursue pleasure, is common among individuals with cocaine use disorder (CUD) and may contribute to poor treatment outcomes. This blunted emotional experience may extend beyond diminished positive affect to include reduced sensitivity to negative …
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Measurement Of Anhedonia In The Chick Anxiety-Depression Model
Anhedonia, the loss of pleasure in previously pleasurable activities, is one of the cardinal features of depression. To further validate the chick anxiety-depression model, the current study aimed at quantifying anhedonia as well its reversal with pharmaceuticals. The first goal was to identify a …
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Hedonics, Reward Prediction, and Reinforcement Learning in Schizophrenia: Relationships to Anhedonia and Avolition
<p>Anhedonia (a reduced experience of pleasure) and avolition (a reduction in goal-directed activity) are common features of schizophrenia that have substantial effects on functional outcome, but are poorly understood and treated. Here, we examine the potential contributions of three processes …
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Characterizing Reward Function During Social Feedback: Associations with Anhedonia in Socially Anxious Adolescents
… clinical relations between reward markers and anhedonia; and (3) Investigate if elevated levels of baseline prior exposure to stress (i.e., peer victimization) are associated with the degree of ventral striatum suppression and anhedonia symptoms in a social stress context. A total of 29 …
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Peripheral Inflammation and Activity within Corticostriatal Reward Circuitry: Interactive Roles in Components of Anhedonia during Adolescence
… experience insufficient treatment response. Anhedonia often is observed in treatment-resistant depression and severe presentations of depression, suggesting that mechanisms underlying anhedonia may be important treatment targets. However, anhedonia is among the most challenging psychiatric …
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The Limits of Perceived Control: Novel Task-Based Measures of Control under Effort and in Anhedonia
… control in relation to self-reported symptoms of anhedonia and found that responsivity to personal control was diminished in those with higher levels of anhedonia. Together these studies examined factors associated with limitations in appetitive personal control and suggest avenues for future …
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Anxiety and Anhedonia in Major Depressive Disorder: The Contributing Roles of Neuroticism, Cognitive Control, and Reward Learning
Higher levels of anxiety and higher levels of anhedonia in Major Depressive Disorder (MDD) are two clinical presentations linked to poorer depression treatment outcomes. However, the mechanisms contributing to these symptom presentations remain unclear. Neuroticism, impaired cognitive control, and …
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Stress and Reward Function in Concurrent Depression and Chronic Cannabis Use
… responses and reward processing underlying anhedonia, which may be putative processes through which depression outcomes are worsened with chronic cannabis use. This investigation utilized a prospective design to examine differences in depression, functioning, perceived stress, and facets …
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Association between the magnitude of the immune response and recurrent major depression disorder in humans and depression-like behavior in animals
… MDD (rMDD) and their current symptoms of anhedonia. The potential moderating role of women’s history of childhood abuse was also examined. Study 2 and 3 focused on animal models of the influence of adolescent stress on LPS-induced changes in adult anhedonic behavior (Study 2) and …
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Motivation to expend physical and cognitive effort as predictors of functioning in major depression
… were assessed on a brief cognitive battery, anhedonia, depression severity, and functional impairment. Results: MDD participants made marginally fewer choices to expend high effort for large relative to small incentives than healthy comparison participants across both effort tasks. Lower …
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Racial discrimination and internalizing psychopathology in African Americans: examining cognitive and affective mechanisms
… of anxious arousal, anxious apprehension and anhedonia. The overarching model proposed that frequent exposure to racial discrimination (i.e., blatant racism, racial microaggressions, and gendered racial microaggressions) may lead to anxious arousal, anxious apprehension and anhedonia through …
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Stress and inflammation regulate the kynurenine pathway dioxygenases in a glia‐ and tissue‐specific manner
… and neuron-derived Ido1 to inflammation-induced anhedonia-like behavior reveling that myeloid-derived Ido1 contributes to inflammation-induced anhedonia. Together, the data highlight glia- and tissue-specific DO regulation by stress and inflammation, and cell-specific contributions of Ido1 to …
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Novel insights into the role of the GABAB receptor in depression and anxiety
… mice exhibited early-life stress-induced anhedonia, a core symptom of depression, while GABAB(1b)-/- mice exhibited a more resilient phenotype. Moreover, when compared with wildtype or GABAB(1a)-/- mice, GABAB(1b)-/- mice that underwent maternal separation exhibited enhanced stressinduced …
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Assessing and remediating altered reinforcement learning in depression
… understand how symptom clusters of depression (anhedonia and negative affect) were related to neural and behavioral measures of learning (Study 1, in Paper 1), how these alterations changed with improvement in symptoms after cognitive behavioral therapy (Study 2, in Paper 1), and how learning …
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The Association Between Cannabis Use and Reward Processing, and the Role of Adolescent Vulnerability
… users. Maladapted reward processing, such as anhedonia and apathy, is a cross-diagnostic symptom in psychiatric disorders, including substance use disorders. Finally, adolescents may be particularly vulnerable to adverse effects of cannabis, due to the important socio-emotional, cognitive, and …
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Teaching Mindfulness to Individuals with Schizophrenia
… in relation to positive symptoms, decreased anhedonia and associated distress, and increased quality of life. Also predicted was that for individuals where mindfulness ability improved over sessions, the participant would also report associated clinical improvement on the quantitative outcome …
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Teaching Mindfulness to Individuals with Schizophrenia
… in relation to positive symptoms, decreased anhedonia and associated distress, and increased quality of life. Also predicted was that for individuals where mindfulness ability improved over sessions, the participant would also report associated clinical improvement on the quantitative outcome …
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Longitudinal coupling of emotional wellbeing in parent-adolescent dyads: evaluating the role of daily life positive affect socialization processes
… between parental depressive symptoms and anhedonia and parental daily-life enhancing and dampening responses to youth positive affect. Study 2 examined associations between parental enhancing and dampening and trajectories of youth positive affect, negative affect, and depressive symptom …
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An investigation of automatic affective processing : behavioral correlates in schizophrenia and neural correlates in healthy adults
… affective priming was associated with increased anhedonia. In contrast, increased cognitive priming was associated with increased disorganized and negative speech symptoms. Overall, these results suggest that there is an automatic affective processing deficit in schizophrenia, and this deficit is …
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