Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 17 of 17 for “"Angiotensin-converting enzyme inhibitors"”.
-
The effects of angiotensin-converting enzyme inhibitors as a pharmacological treatment for Dupuytren’s disease
… factors. There is some evidence that Angiotensin II (ANGT II) may be associated with this disorder and that blockers of ANGT II may help in treating this disease. This study was designed to investigate the presence of ANGT II receptors 1 (AT1) and 2 (AT2) in myofibroblasts derived from …
-
Revealing the Mechanism Underlying the Beneficial Effects of Angiotensin-Converting Enzyme Inhibitors in a Drosophila Alzheimer’s Disease Model
… several studies have implicated the renin-angiotensin system (RAS), known to regulate blood pressure, as a possible therapeutic target for AD. RAS inhibiting drugs, including angiotensin-converting enzyme inhibitors (ACE- Is), have been shown to reduce the incidence and progression of AD. …
-
The effects of angiotensin converting enzyme inhibitors (ACEI) on human N-acetylseryl-aspartyl-lysyl-proline (AcSDKP) levels : a systematic review
… mechanism for the heightened fibrotic state. Angiotensin converting enzyme inhibitors (ACEI), which increase Ac-SDKP levels with antifibrotic effects in animal models, are candidate drugs for preventing constrictive pericarditis if they can be shown to have similar effects on AcSDKP and …
-
The kidney in diabetes mellitus : urinary transfer in excretion, hypertension, the Renin-Angiotensin-Aldosterone system, and the role of angiotensin converting enzyme inhibitors in therapy
… Interventional studies with lisinopril, an angiotensin converting enzyme [ACE] inhibitor, in microalbuminuric and macroalbuminuric diabetic subjects show a reduction in TER independent of reduction in blood pressure. Data are presented suggesting a role for altered renal tubular function in …
-
Genetic and biochemical analysis of ACE inhibitor-induced angioedema in black and coloured South Africans
Angiotensin converting enzyme inhibitors (ACEi) are routinely used as first line treatment for hypertensive patients because of their protective effects against heart and kidney disease. Despite their clinical benefits, ACEi used is associated with adverse side effects such as life threatening …
-
ABSENCE OF V1AR ALTERS CARDIAC FUNCTION AT BASELINE AND FOLLOWING ACUTE CARDIAC INJURY
… pressure, such as the activation of the renin-angiotensin-aldosterone system (RAAS) and the sympathetic nervous system. Current treatment guidelines recommend using drugs that block β-adrenergic receptor (βAR) signaling (e.g. β- blockers) or RAAS signaling (e.g. angiotensin receptor …
-
Clinical assessment of arterial stiffness
… disease (PAD), chronic kidney disease (CKD) and angiotensin converting enzyme inhibitors (ACE-Is). A reproducibility study demonstrated good reproducibility. A study of healthy subjects demonstrated a stronger relationship with age for arterial stiffness than intima media thickness (IMT). Case …
-
Achievement of secondary prevention goals 6 to 9 months after Acute Coronary Syndrome : a retrospective, cross-sectional analysis
… medications (aspirin, HMG-CoA reductase inhibitors [statins], beta-blockers and angiotensin-converting enzyme inhibitors [ACEIs] or angiotensin receptor blockers [ARBs]) and smoking cessation in patients after acute coronary syndromes. At present, little is known about adherence to …
-
Combination Treatment of Angiotensin-II Receptor Blocker and Angiotensin-Converting-Enzyme Inhibitor in Non-Diabetic Renal Disease on Effect of Reducing Proteinuria
BACKGROUND: The fact that angiotensin-converting enzyme inhibitors(ACEI) and angiotensin receptor blockers(ARB) antagonize the renin-angiotensin system at different levels suggests that these agents, already confirmed by clinical benefit in retarding the progression of chronic renal disease, may …
-
The Morbidity & Mortality of Prevalent Heart Failure
… of beta-adrenergic blockade (β-blockers), angiotensin-converting-enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARB) to the most tolerable levels in order to reach target dosages, as recommended by the Heart Failure Society of America (HFSA). Patients were classified into …
-
Biomechanics of Cardiac Remodelling in Heart Failure
… of SHRs were compared with SHRs treated with angiotensin-converting enzyme inhibitors (TSHRs), as well as Wistar-Kyoto (WKY) controls. These animals were studied at three time-points, 3 months (mo), 14 mo and 21 mo. Each animal underwent cardiac magnetic resonance imaging (MRI) and in vivo …
-
Commonly used medications and survival from ovarian cancer
… interest (statins, antihypertensives [including angiotensin converting enzyme inhibitors (ACEIs), beta blockers (BBs), calcium channel blockers (CCBs) and thiazide diuretics (TDs)]) was defined as two or more fills for a given medication class during the year after diagnosis. Ovarian …
-
The Effect of Withdrawal of Angiotensin II Blockers on Serum Creatinine and Potassium in Patients with Chronic Kidney Disease
BACKGROUND: Renin-angiotensin system (RAS) blockers have been used to delay the progression of various renal diseases, but these medications cause hyperkalemia and the elevation of serum creatinine which impede the continuation of the medications. So far, there have been no data which observe the …
-
N-Glycosylation profiles as a risk stratification biomarker for Type II Diabetes Mellitus and its associated factors
… status at follow-up. Many participants using angiotensin converting enzyme inhibitors achieved desired targets for blood pressure control while statins were effective for control of plasma lipids (Study IV). At a population level, the variability of N-glycan structures ranged from 11% to 56% …
-
The effects of centrally acting ACE inhibitors on the rate of cognitive and functional decline in dementia: a KDD approach
… is also growing evidence that centrally acting angiotensin converting enzyme (ACE) inhibitors, which cross the blood-brain barrier, are associated with a reduced rate of cognitive and functional decline in dementia, especially in Alzheimer’s disease (AD). The aim of this research is to …
-
Flow Chemistry Guided by Computer-Aided Synthesis Planning
… a strategy for the continuous synthesis of angiotensin converting enzyme inhibitors, including quinapril and enalapril. This strategy was informed by ASKCOS, a computer-aided synthesis program, and developed manually using bench-top flow reactors as well as batch chemistry techniques. An …
-
Pronóstico de la insuficiencia cardíaca con fracción de eyección preservada tratada con inhibidores del sistema renina- renina-angiotensina
… tratamiento con inhibidores del sistema renina-angiotensina (ISRAs), inhibidores de la enzima convertidora de angiotensina (IECAs) o bloqueantes de receptores de angiotensina (BRAs), sobre el pronóstico de pacientes con insuficiencia cardíaca y fracción de eyección preservada (ICFEp). Objetivos. …