Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Angiostatin"”.
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The effect of angiostatin on the endothelial cell cycle
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Biology, 1998.
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Identifizierung und Isolierung von Angiostatin aus dem Urin bei Patienten mit Prostatakarzinom
… Inhibitor der Angiogenese, den er Angiostatin nannte, nachzuweisen und zu isolieren. Uns gelang es, im Western-Blot Angiostatin und Angiostatin-Spaltprodukte sowohl aus dem Urin von PCa-Patienten als auch aus dem Urin gesunder Probanden nachzuweisen und zu isolieren. Die …
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Cyclooxygenase-2 and prostaglandins in human endometrial function
… cleave plasminogen to the antiangiogenic factor angiostatin. Hence, we investigated the generation of angiostatin from plasminogen in conditioned media collected from cyclooxygenase-2 sense, cyclooxygenase-2 antisense and wild type cells. The cleavage of angiostatin from plasminogen was markedly …
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Each one teaches one: characterizing active forms of proteins by single molecule force spectroscopy
… Chapter 5 and Chapter 6). The work conducted on angiostatin focused on the characterization of the relationships between the mechanochemical properties and the mechanism of action of the angiostatin protein, and most importantly their intertwining with the further layer of complexity due to …
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Proteolyse-induzierte Spaltprodukte des Plasminogens
… Counterpart besteht aus den Kringeln1-4. Es wird Angiostatin genannt, weil es hemmend auf die Neubildung von Gefäßen wirkt. Im Rahmen dieser Arbeit sollte untersucht werden, ob Miniplasminogen unter pathologischen Bedingungen wie Sepsis, Peritonitis und Tumorerkrankungen auftritt, um daraus …
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Antiangiogenic and proteolytic activities of prostate-specific antigen
… activity of PSA was not mediated by angiostatin-like fragments generated by the cleavage of plasminogen. The results of this thesis established that the proteolytic activity is necessary for the antiangiogenic activity of PSA and that the antiangiogenic activity can be enhanced by …
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Effect of resection of localised pancreatic cancer on tissue-factor promoted pathways of thrombosis, cell invasion and angiogenesis
… was a significant decrease of angiopoietin-1, angiostatin/plasminogen, PDGF-AA, PDGF-AB/PDGF-BB and VEGF post-operatively. This result was supported by ELISA analysis of 29 samples and 14 controls that also showed significantly higher levels of VEGF in pancreatic cancer sera versus control …