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Showing 1 to 4 of 4 for “"Angeli's Salt"”.
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Acyloxy Nitroso Compounds as HNO Donors and Their Reactions with Thiol and Heme Containing Proteins
… failure through the ability of the HNO donor, Angeli's salt (AS), to evoke positive inotropic effects in canine cardiac muscle. The release of nitrite during decomposition limits the use of AS requiring other HNO sources. Acyloxy nitroso compounds hydrolyze to HNO, while the rate of …
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Reactions of Nitroxyl and Nitrite in Blood
… scavenge NO. We investigated the effects of Angeli's Salt (AS, Na<sub>2</sub>N<sub>2</sub>O<sub>3</sub>), a nitroxyl (HNO) and nitrite (NO<sub>2</sub><super>-</super>) donor, on plasma Hb oxidation, and on the vasoactivity of plasma Hb. Both HNO and nitrite are known to oxidize oxyHb to …
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The Role of Phospholamban Cysteines in the Activation of the Cardiac Sarcoplasmic Reticulum Ca2+ Pump by Nitroxyl (HNO)
… (ER) microsomes. Samples were treated with Angeli's salt (an HNO donor) to determine the role of each PLN cysteine residue in the mechanism of SERCA2a activation by nitroxyl. Using a standard phosphate activity assay and SDS-PAGE/immunoblot techniques, we determined that the PLN cysteine …
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Phosphine-Mediated Ligations: A Powerful and Versatile Method for the Selective Chemical Detection of Nitroxyl
Nitrogen oxides are a class of small molecules with profound physiological and environmental consequences. Nitric oxide (NO), the most well-known of these, is a key endogenous signaling agent effecting platelet disaggregation and vasorelaxation. Nitroxyl (HNO), the product of NO reduction and …