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Showing 1 to 20 of 59 for “"Anesthetics"”.
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Local Anesthetics in Post-Operative Endodontic Pain
… for patients who received long-acting local anesthetics. Male patients who received bupivacaine reported less post-operative pain than females who received bupivacaine. The trends observed in this study suggest that long-acting local anesthetics are effective in the management of …
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Shedding Light On General Anesthesia: Uncovering The Molecular Mechanisms For Propofol And Volatile Anesthetics
General anesthetics have played a pivotal role in the history of medicine. Despite accounts of their use within the earliest of human records, our understanding of anesthetic mechanisms remains unclear. Understanding these molecular mechanisms would be a significant advance toward enhanced drug …
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Do Buffered Local Anesthetics Provide More Successful Anesthesia Over Non-Buffered Solutions in Patients Requiring Dental Therapy? – A Systematic Review & Meta-Analysis.
… The pH of commercially available local anesthetics (LAs) is purposefully low (pH 3–4). Decreasing the pH extends the shelf life of the solution and prevents its early oxidation. However, a low pH may produce a burning sensation on the injection site, a slower onset of anesthesia, and a …
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Wirkung von milder Hypothermie auf den negativ inotropen Effekt von Halothan, Isofluran und Sevofluran auf ventrikuläres Kaninchen-Myokard
… the negative inotropic response of the volatile anesthetics halothane, isoflurane and sevoflurane on ventricular rabbit myocardium. Measured parameters were contractility, the timing of contractions, response to the raise of extracellular calcium concentrations and the first contraction after a …
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Einfluss der Inhalationsanästhetika Sevofluran und Desfluran auf die Ausbildung von Adhäsionsmolekülen auf Granulozyten in vitro
Volatile anesthetics are reported to reduce ischemia-reperfusion injury. One suggested mechanism was the attenuated expression of CD11b on activated neutrophils after exposure to volatile anesthetics. However, neutrophil adhesion to vascular endothelium is a multistep process involving several …
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A Pharmacological Analysis of the Ionic Channels of Nerve
… the nodal membrane. Other drugs including local anesthetics, some general anesthetics, and veratrine alkaloids exerted moderately specific effects on the components of current. The anesthetics abolished sodium currents and the veratrine alkaloids enhanced sodium currents and prolonged their time …
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Unsupervised tracking and automated analysis of multi-population neural activity under anesthesia
Volatile anesthetics play an essential role in the practice of modern medicine due to their widespread use in general anesthesia. Research on anesthetics has mainly involved studies of molecular effects on ion channels and receptors, or on alterations of gross neural activity across large brain …
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Veränderung der Hämodynamik durch die Kombinationsnarkose aus Xenon und Isofluran im Vergleich zu der aus Xenon und Sevofluran an Schweinen
… taken as baseline values. Therefore the volatile anesthetics were administered at 1.0, 1.3 and 1.6 MAC. After that measurements together with xenon and one of the volatiles were performed. Xenon was delivered at increasing levels (15%, 30%, 40%, 50% and 65%) and each xenon concentration was …
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The Importance of the Multicomponent Display in Sexual Selection of Black Morph Girardinus metallicus (Pisces: Poeciliidae)
… via chemical anesthesia; however, the anesthetics may alter the resulting measurements, for example by darkening the skin. <em>Girardinus metallicus</em>, a poeciliid fish endemic to Cuba, has a multicomponent courtship and aggressive display. Black morph males exhibit black ventral …
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Development and Applications of Opioids Alternatives for Pain Management
… on tetrodotoxin (TTX) and capsaicin as novel anesthetics. Acute post-surgical pain typically lasts 5-7 days, while long-term pain management can span up to 12 weeks. Opioids are commonly used but are linked to serious side effects, including addiction, nausea, cognitive impairment, and fatal …
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Investigations on the Use of Ion Mobility Spectrometry for Clinical Chemistry Applications
… of physiologically active substances, including anesthetics, illicit drugs, and their metabolites. The IMS characteristics of animal tissues and other compounds such as amino acids and proteins were determined. Quality assurance and control procedures were developed for specific quality data …
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MAC-Wert-Bestimmung von Sevofluran bei unterschiedlichen Xenonkonzentrationen an 10 Schweinen
… the combination of Xe with other inhaled anesthetics. In the existing literature, the reported relationships between the effects of volatile and gaseous anesthetics are not uniform. The basic question whether such combinations will act additively or show partial antagonism has not been …
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