Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 37 for “"Anaesthesiology"”.
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The peri-operative pain management of total abdominal hysterectomy patients at an academic hospital
… standardised protocols or collaboration between Anaesthesiology and Gynaecology in managing acute postoperative pain. Patients were not uniformly advised regarding the post-operative expectations of their pain and non-pharmacological measures were not emphasised by the treating team. Despite …
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Postoperative outcomes associated with procedural sedation conducted by physician and non-physician anaesthesia providers: findings from the prospective, Observational African Surgical Outcomes Study (ASOS)
Background There is an unmet need for essential surgical services in Africa. Limited anesthesia services are a contributing factor. Non-physician anesthesia providers are utilized to assist with providing anesthesia and procedural sedation in order to make essential surgeries available. There is a …
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The association between perioperative risk factors and the method of anaesthesia, and maternal and neonatal outcomes following caesarean delivery in Africa: a sub-study of a 7-day prospective observational cohort study
Background Maternal and neonatal mortality is high in Africa. The African Surgical Outcomes Study found that maternal mortality following caesarean delivery in Africa is 50 times higher than in highincome countries, and independently associated with obstetric haemorrhage and anaesthesia …
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Documentation of spinal anaesthesia technique and block level at caesarean section
Background The ease of administration and relative safety of spinal anaesthesia has made this the preferred technique for elective and many emergency caesarean sections. Complications include incomplete sensory block, resulting in intraoperative breakthrough pain, which is commonly associated with …
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A multicentre cross-sectional descriptive study evaluating the cardiovascular risk profile of preoperatively identified patients with hypertension
Background. The prevalence of hypertension in adults in South Africa (SA) is 35%. Hypertension is the most important modifiable risk factor for cardiovascular (CV) and chronic kidney disease (CKD) in subSaharan Africa. However, 49% of people are unaware of their blood pressure status. Screening for …
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A prospective study of paediatric preoperative fasting times at Red Cross War Memorial Children's Hospital
Background. Fasting for liquids and solids is recommended prior to procedures requiring anaesthesia, to reduce the risk of pulmonary aspiration. Children often experience excessive fasting, which is associated with negative physiological and behavioural consequences, and patient discomfort. The …
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The association between preoperative anaemia and surgical mortality and morbidity in South African surgical patients
Background: In high-income countries, preoperative anaemia has been associated with poor postoperative outcomes. To date, no large study has investigated this association in South Africa. The demographics of South African surgical patients differ from those of the European and Northern American …
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A systematic review of outcomes associated with withholding or continuing angiotensinconverting enzyme inhibitors (ACE-I) and angiotensin receptor blockers (ARB) prior to noncardiac surgery
Introduction The global rate of major noncardiac surgical procedures is increasing annually, and of those patients presenting for surgery increasing numbers are taking either an angiotensin-converting enzyme inhibitor (ACE-I) or an angiotensin receptor blocker(ARB). The current recommendations …
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Retrospective observational study of the choice of anaesthesia for caesarean section in patients with eclampsia
Background Anaesthesia for ceasarean section (CS) in women with eclampsia is a major clinical challenge, and there are limited data concerning the rationale for the choice of technique, and the short-term outcomes. A retrospective audit was performed on practice at a tertiary referral centre in …
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Timing of complications following elective craniotomies
Background: Conservative prolonged observation periods after elective craniotomies with admission to neurosurgical higher or intensive care units (ICU) have been the norm for many decades. This practice is neither evidence based nor a cost-effective use of medical resources. This observational …
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Coagulation in the HIV-positive pregnant patient: A thromboelastographic study
Human immunodeficiency virus (HIV)infection is associated with haematological changes, including thrombocytopaenia. Pregnancy induces a hypercoagulable state. There are limited data on the coagulation status of women with term pregnancy and HIV receiving anti-retroviral medication. Regional …
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The effect of patient warming on perioperative cardiovascular outcomes in interventional clinical trials: A systematic review and meta-analysis
BACKGROUND: Perioperative cardiovascular events are a common contributor to perioperative morbidity and mortality. Patient warming affects the cardiovascular system in various ways and may protect against cardiovascular events. We aimed to estimate the effect of active patient warming on …
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A study of the prevalence of preoperative anaemia and iron deficiency in adult elective surgical patients in hospitals in the western cape province, South Africa. “A multicentre prospective observational study of the prevalence of preoperative anaemia and iron deficiency in adult elective surgical patients in hospitals in western cape province, South Africa.”
Background. Preoperative anaemia has been shown to be an independent risk factor for postoperative morbidity and mortality. Iron deficiency is the leading cause of anaemia globally. There are limited data describing the burden of perioperative anaemia and the relative contribution of iron …
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A Systematic Review and narrative synthesis of the methods used to teach adult airway management skills to novices
Background: Airway management is an essential skill for healthcare providers across many disciplines. Inadequate airway management leads to adverse events and deaths. Clear guidance on the use of evidence-based educational methods to train novice airway managers is limited. Best evidence suggests …
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Paediatric out-of-theatre procedural sedation at a tertiary children's hospital: A prospective observational study
Background: This tertiary referral centre is one the largest paediatric hospitals in Africa. Despite an increasing number of surgical and diagnostic procedures being performed annually, a formal out-of-theatre sedation service does not exist. Procedural sedation and analgesia (PSA) is an important …
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A quality improvement project evaluating the perioperative implementation of a hypertension management protocol by anaesthesiologists at seven government hospitals in the Western Cape. “a multi-center, cross-sectional quality improvement project: the peri-operative implementation of a hypertension protocol by anesthesiologists”
BACKGROUND: Hypertension is a common risk factor for cardiovascular morbidity and mortality, with a high prevalence in patients presenting for elective surgery. In limited resource environments, patients have poor access to primary care physicians, limiting the efficacy of life-style modification …
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Aspects of sepsis/SIRS - An experimental study on fluid therapy, vitamin C and plasma volume in increased permeability
In sepsis, after major surgery or severe trauma, the human body may suffer from various degrees of generalized inflammation, a syndrome called Systemic Inflammatory Response Syndrome (SIRS). One feature of SIRS is increased capillary permeability, caused by disruption of the capillary endothelium …
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Aspects of bleeding complications and hemostasis at central line insertion and mild induced hypothermia
Bleeding complications range from 0.5 to 1.6% in connection with central venous catheter insertions but are more frequent in patients with bone marrow failure and severe thrombocytopenia. Although supportive evidence is scarce, prophylactic platelet transfusion is sometimes performed in these …
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Circulating proteoglycans and glycosaminoglycans during critical illness
The endothelial glycocalyx is the carbohydrate rich inner layer of the blood vessels. Important components of the glycocalyx are the proteoglycans with their attached glycosaminoglycans. At this location these molecules contribute to the adhesion and transport of leucocytes to inflamed tissue, the …
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Viscoelastic haemostatic assays and fibrinogen concentration tests during haemodilution: The effects of fibrinogen and factor XIII
Background: The efficacy of concentrates of fibrinogen and factor XIII in hypothermia and haemodilution has not yet been completely investigated. Clauss methods have not previously been evaluated perioperatively. Methods: Coagulation was assessed with rotational thromboelastometry (ROTEM) or free …
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