Global ETD Search
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Showing 1 to 1 of 1 for “"Amyotrophic Lateral Sclerosis, Motoneuron, Astrocyte, Endothelin, reactive gliosis"”.
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Endothelin-1 is over-expressed in Amyotrophic Lateral Sclerosis and induces Motor Neuron cell death
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder characterized by progressive loss of motor neurons (MNs) and astrogliosis. Recent evidences suggest that factors secreted by activated astrocytes might contribute to degeneration of MNs. We focused on endothelin-1 (ET-1), a peptide …