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Showing 1 to 2 of 2 for “"Amyloidfibrillen"”.
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Bedeutung eines hydrophoben Seitenkettenstapels für Stabilität, Faltung und Struktur des P22 Tailspikeproteins
… sind ebenfalls typische Kennzeichen von Amyloidfibrillen, die bei Proteinfaltungskrankheiten wie Alzheimer, der Creutzfeld-Jakob-Krankheit, Chorea Huntington und Typ-II-Diabetes gebildet werden. Es wird vermutet, dass die hohe Stabilität des Tailspikeproteins und auch die der …
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Identification and charaeterization of IAPP-derived inhibitors of cytotoxic self-assembly and amyloidogenesis of islet amyloid polypeptide (IAPP) and beta-amyloid peptide (A beta)
Protein aggregation into cytotoxic oligomers and fibrils in vivo is linked to cell degeneration and the pathogenesis of more than 25 uncurable diseases, which are often called amyloid diseases, while the high aggregation propensity and insolubility of several bioactive polypeptides and proteins in …