Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Amyloid beta 42"”.
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The Role of Neuroinflammation in Alzheimer's Disease
… to test the inflammatory potential of synthetic amyloid beta 42 aggregates. In conjunction with a liposome-permeability assay and an immunoprecipitation assay, this assay has been used to validate a proprietary amyloid beta 42 antibody from MedImmune (now AstraZeneca). Most neuroinflammation …
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Mitochondrial Dysfunction: A Mechanistic Link in the Progression from Normal Aging to Sporadic Alzheimer’s Disease
… mitochondrial function and intra-synaptic amyloid beta 42 (Aβ42) levels was also observed. Additionally, by utilizing a mouse model expressing non-mutant humanized Aβ [humanized Aβ knockin (hAβ KI) mice, also referred to as a model of late-onset AD in previous literature], we identified …
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Early Diagnosis of Alzheimer's Disease and Studying Binding to Opioid Receptors using Whispering Gallery Mode Microtoroid Biosensors
… of dementia characterized by the deposition of amyloid plaques in the brain. We used microtoroids functionalized with amyloid-beta 42 (Aβ42) antibodies to measure the levels of Aβ42 in cerebrospinal fluid for healthy, cognitively impaired, and AD positive groups. Our results demonstrated higher …
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Investigating the Differences between Neuropsychological and Physiological Markers in a PTSD-only Group Among Vietnam Veterans
… lower superior parietal volume, and lower amyloid positivity in people with PTSD, although preliminary results have not indicated PTSD as an increased risk factor for AD (Weiner et al., 2017). Therefore, further assessment of the differences between CSF amyloid, CSF ptau, and PTSD symptoms, …
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Protein-lipid interactions in molecular pathways of Parkinson’s and Alzheimer’s diseases
… involved in the pathogenesis of AD and PD are amyloid β 1–42 (Aβ42) and α-synuclein (αS), which cause the toxicity in AD and PD through aberrant interactions with lipid membranes. Despite current significant effort, the link between αS-/Aβ42-membrane interactions and disease mechanisms remains …