Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"Amphetamines"”.
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Amphetamines and Western Australian detainees: A social profile
The current study utilised data collected from the Australian Institute of Criminology’s project known as Drug Use Monitoring in Australia (DUMA). The DUMA project examined detainees’ social demographics and past and present drug use, at various Australian sites. The current study examined …
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Age- and sex-specific effects of amphetamines on cognition and serotonin in the orbitofrontal cortex
Use of amphetamines is a global health problem associated with significant social and financial burdens. Worldwide, amphetamines are second only to marijuana and opiates, respectively, for most abused illicit drug and highest prevalence of addiction. Epidemiological data reveal that adolescent and …
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Modeling and Mapping Addiction in the Zebrafish, Danio rerio
… the release of dopamine. Drugs of abuse, like amphetamines, for instance, increase dopamine availability to trigger reward circuits, leading to addiction behaviors. The mechanisms by which amphetamines stimulate dopamine release among reward neurons and the addiction behaviors expressed have …
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Alcohol and amphetamine dependencies convoluted with anorexia and bulimia nervosa
… are initially motivated to use alcohol and amphetamines because of underlying issues involving body dissatisfaction and weight reduction associated with Anorexia and Bilimia Nervosa. Current literature reveals similarities among chemical dependencies and eating disorders.
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Genetic Alterations Associated with Attention Deficit Hyperactivity Disorder
… and the subsequent use of prescription amphetamines which may lead to long term developmental cognitive alterations. Previous literature has identified ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 3 (ST3GAL3) as a possible genetic component underlying ADHD. This study uses Loop …
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Adolescent Involvement in Alcohol and Drug Use
… would include alcohol, tobacco, cannabis, amphetamines, barbiturates, cocaine, the opiates and also the hundreds of medicines to be found in chemist shops. Our society is a drug taking society, that is a pill for every ill. There are drugs for sleeping, headaches, stomach ailments, almost …
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The detection of drugs of abuse in biological matrices using enzyme-linked immunosorbent assay and liquid chromatography-tandem mass spectrometry
… The LC-MS-MS method analysed for and detected amphetamines in samples that were not tested for amphetamines by GC-MS. In one sample that was tested by both methods, amphetamine was detected in the root sample by LC-MS-MS where GC-MS failed to detect it. Also a greater concentration of …
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An evaluation of analytical procedures for detection of drug abuse with particular reference to opiates.
… of a pre-employment drug screening programme for amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine and opiates involving some 1400 subjects by enzyme immunoassay, carried out by the author, are reported. The corresponding confirmatory tests by GC-MS on samples screening positive …
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Comparison of Liquid-Liquid Extraction and Solid Phase Extraction of Mephedrone
… has become the knockoff replacement for amphetamines. This experiment focused on comparing liquid-liquid extraction to solid phase extraction to determine if there was a difference and which was more efficient. Synthetic urine samples were spiked with mephedrone, extracted using both …
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The Effects of Amphetamine Exposure on Neurodevelopment and Behavior in Early Life Stages of Danio Rerio
<p>Amphetamines are frequently prescribed to young children for attention deficit hyperactivity disorder (ADHD). Due to the recent rise in ADHD diagnoses and the resulting increase in amphetamine intake in children, we investigated how amphetamine exposure impacts the development of stereotyped …
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Young people, school exclusion and substance abuse
… and solvents. Other drugs such as ecstasy, amphetamines and LSD were also used but to a lesser extent. Poly-substance use was also found within the sample. For some, substance using behaviours began prior to exclusion from school. The young people self-reported, however, that these …
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‘I quit heroin for meow’: A qualitative study of the use of new psychoactive substances among problem drug users in South Wales
… the repertoires of long-term users of heroin, amphetamines and cocaine (often referred to as ‘problem drug users’). In the UK, the first reports of NPS use among problem drug users came from South Wales, in the autumn of 2012. Albeit anecdotally, drug agencies, local newspapers and the police …
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Papain: a Novel Urine Adulterant.
… FPIA analysis of other frequently abused drugs: amphetamines, barbiturates, benzodiazepines, cocaine, opiates, and phencyclidine, along with gas chromatography/mass spectrometry (GC/MS) of THC-COOH and high pressure liquid chromatography/ultraviolet detection (HPLC/UV) of nordiazepam was …
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Dopamine Uptake Inhibition Potency Fluctuations of Cocaine at the Dopamine Transporter
… resulting in physical dependence on the drug. Amphetamines are psychotomimetics that act as substrates at the DAT and potentiate dopaminergic neurotransmission leading to addiction. It was previously reported that a conservative glutamate-for-aspartate substitution in transmembrane 1 domain of …
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Computational Ligand-Based CNS Therapeutic Design: The Search for Novel-Scaffold Norepinephrine Transporter Inhibitors
… drugs of abuse such as cocaine and the amphetamines. Due to a lack of crystallographic MAT data, it is unclear as to which of two MAT protein ligand binding sites these drugs bind, hindering knowledge of the specific binding modes of MAT ligands. In this study an in silico pharmacophore …
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Analysis of Illicit Drugs, Their Metabolites and Other Micropollutants in Water by Liquid Chromatography Tandem Mass Spectrometry
… drugs found in the wastewater were cannabinol, amphetamines and cocaine. The concentrations of these drugs are being monitored at regular time intervals for the purpose of determining the total drug consumption of a targeted population. This type of drug testing (of small, demographically …
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Diagnostic use of hair analysis for the detection of misuse of amfetamines and cannabinoids
… (2:1 v/v) and PFPA / PFPOH (1:0.75 v/v) for amphetamines and cannabinoids, respectively. The results showed good peak shape, good chromatographic resolution and good sensitivity for amfetamine (AF), methamphetamine (MA), 3,4-Methylenedioxyamfetamine (MDA), 3,4-Methylenedioxymethamfetamine …
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Impurity profiling and synthesis of precursors to the hallucinogenic amphetamine DOB
… of a range of several other hallucinogenic amphetamines. A number of different routes to both 2,5‐P2P and 4‐Br‐2,5‐P2P were investigated. For each of these routes, the impurities produced were carefully isolated. Following isolation, the impurities were fully characterised (by 1H‐NMR/13C‐NMR …
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Hair analysis for drugs of abuse
… identification and quantification of opiates, amphetamines, ketamine, cannabis, cocaine, benzodiazepines, antidepressants, antipsychotics, and anabolic steroids in hair were developed using gas chromatography–mass spectrometry (GC-MS), liquid chromatography–tandem mass spectrometry (LC-MS/MS) …
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